, 2014 The standard of care for patients suffering cancer often includes treatment with nucleoside analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters and, after enzymatic activation (often one or more phosphorylation steps)
Balzarini, Jan +2 more
core
Metabolic Imaging to Assess Treatment Response to Cytotoxic and Cytostatic Agents [PDF]
, 2016 For several decades, cytotoxic chemotherapeutic agents were considered the basis of anti-cancer treatment for patients with metastatic tumors. A decrease in tumor burden, assessed by volumetric computed tomography (CT) and magnetic resonance imaging (MRI)
Natalie J. Serkova, S. Gail Eckhardt
core +2 more sources
Incidence of drug-induced liver injury in medical inpatients [PDF]
, 2018 Objectives: Drug-induced liver injury (DILI) is a common concern. However, data on DILI epidemiology in inpatients are sparse. Methods: To investigate the incidence of DILI, we screened all patients in the pharmacoepidemiological inpatient database ...
Cavallaro, Marzia +6 more
core
Perspectives and Prospects in the Chemotherapy of Gastrointestinal Cancer [PDF]
, 1967 5-Flourouracil (5-FU) is the best agent for the treatment of all gastrointestinal cancers but should be used with restraint, since severe toxicity does not guarantee increased response or survival time.
Regelson, William
core +1 more source
Cytotoxic Properties of Anthraquinones (Nordamnacanthal and Damnacanthal) from Roots of Morinda Elliptica [PDF]
, 2003 The study on the cytotoxic properties of nordamnacanthal and damnacanthal, the anthraquinones isolated from the roots of Morinda elliptica (family Rubiaceae) were carried out on several cancerous cell lines including CEM-SS (T-lymphoblastic leukaemia),
Saiful Yazan, Latifah
core
Effects of daunorubicin, mitomycinC, azathioprine and cyclosporinA on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines [PDF]
, 2018 Background: We wished to investigate the toxicity of four immunosuppressant and antimetabolic drugs, which are known to influence postoperative wound healing, on three different human ocular cell lines.
Garweg, Justus +2 more
core
A genome scale overexpression screen to reveal drug activity in human cells [PDF]
, 2014 core +1 more source
Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment [PDF]
, 2006 core +1 more source
Working note-book for the practical classes on biochemistry [PDF]
, 2013 БИОХИМИ
Buyanova, S. V., Konevalova, N. Yu.
core
Exploratory analysis of gene aberrations and chemotherapy response: findings from a real-world database in Japan. [PDF]
Br J CancerIshibashi N +5 more
europepmc +1 more source