Results 91 to 100 of about 17,553 (208)
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal +29 more
wiley +1 more source
ABSTRACT Actinic keratosis (AK) is a common premalignant skin condition associated with chronic ultraviolet exposure and an increased risk of progression to cutaneous squamous cell carcinoma (cSCC). Its prevalence rises with age and is influenced by multiple factors, including fair skin phototype and immunosuppression.
Gloria Hoxhallari +10 more
wiley +1 more source
Unusual association of central retinal vein occlusion and breast carcinoma. ABSTRACT Central retinal vein occlusion in 41‐year‐old female patients without conventional risk factors should raise concern for systemic evaluation for underlying malignancy and treatment‐related hypercoagulability.
Hamna Danyal Barry +5 more
wiley +1 more source
ABSTRACT Background There is a growing body of literature suggesting that GLP‐1 receptor agonists (GLP‐1RAs) may be associated with hair loss; however, primary literature is sparse. Additionally, it is not well‐established which types of hair loss may be associated with GLP‐1RA use. Objectives This study aims to assess associations between GLP‐1RAs and
Lauren M. Ching +2 more
wiley +1 more source
Who Should Receive Antimetabolites After Filtering Surgery?
Don't tell me what you think that I should do. What would you do if this were your patient?," and so go the questions about the use of antimetabolites with filtering surgery. In practice, many difficult and unresolved issues remain.
Richard K. Parrish, Parrish, Richard K
core +1 more source
Transcriptomic analysis using a rabbit glaucoma filtration surgery model, combined with in vitro experiments on human conjunctival fibroblasts, demonstrates that mitomycin C induces a senescence‐associated secretory phenotype (SASP)‐like state. These SASP‐like fibroblasts were selectively eliminated by the specific senolytic agent, highlighting their ...
Akitoshi Kimura +12 more
wiley +1 more source
These drugs interfere with the production of nucleic acids by three mechanisms. Some inhibit production of the deoxyribonucleoside triphosphates that are the immediate precursors for deoxyribonucleic acid (DNA) synthesis, thus inhibiting the replication ...
Mark L. Moster, MD; Rod Foroozan, MD
core
Antimetabolites in the nutrition of the silkworm bombyx mori L.-I: niacin and pyridoxine antagonists
Growth inhibition with antimetabolite and its reversal with the metabolite has been employed as a criterion for studying the nutritional requirement of the silkworm for niacin and pyridoxine.
Bhat, J. V., Shyamala, M. B.
core +1 more source
Leftover mitomycin-c sponge causing blebitis
Trabeculectomy is the commonest surgical intervention performed worldwide for the treatment of open-angle glaucoma. However, the use of antimetabolites during trabeculectomy has been associated with various bleb related complications.
Mayuri Khamar +3 more
doaj +1 more source
HBV reactivation incidence varied across immunosuppressive and chemotherapeutic agents. Clinically meaningful HBV reactivation was also observed in patients receiving corticosteroids and conventional immunosuppressive therapies. ABSTRACT Background Data on the incidence of hepatitis B virus reactivation (HBVr) remain limited. In Japan, patients who are
Kazuhiko Ikeuchi +8 more
wiley +1 more source

