Results 111 to 120 of about 17,553 (208)

Nucleoside and nucleotide analogues containing fluorine [PDF]

open access: yes, 1993
The work contained in this thesis is divided into four sections detailing the formation of (diethoxyphosphinyl)difluoromethylene substituted cycloalkanes and alkenes and their chemistry, as well as the syntheses of purine and pyrimidine substituted ...
Parkinson, Nigel Christopher
core  

Computer-assisted microscope analysis of morphonuclear modifications induced by anticancer antimetabolites in cell lines cultured in vitro.

open access: yes, 1994
An original method is proposed for the purpose of discriminating between antimetabolites exhibiting different operating mechanisms. The present work was carried out by means of the digital cell image analysis of Feulgen-stained nuclei cultured in the ...
Atassi, Ghanem   +2 more
core  

ANTIMETABOLITES OF SEROTONIN

open access: yesJournal of Biological Chemistry, 1953
D W, WOOLLEY, E, SHAW
openaire   +2 more sources

Antimetabolites in the treatment of arthritis:current status of the use of antimetabolites

open access: yesNucleosides, nucleotides & nucleic acids, 2004
Rheumatoid arthritis (RA) is an autoimmune disease characterized by a chronic inflammation of the synovial joints and infiltration of blood-derived cells. In daily practice rheumatologists use the antimetabolites methotrexate (MTX) and leflunomide for the treatment of patients with rheumatoid arthritis.
Dijkmans, B A C, Jansen, G
openaire   +2 more sources

A New Electrochemical Sensor for Direct Detection of Purine Antimetabolites and DNA Degradation

open access: yes, 2019
The development of a reliable electrochemical sensor using a hybrid nanocomposite consisting of ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate) functionalized graphene oxide (GrO-IL) and gold nanoparticles (AuNPs) stabilized by chitosan ...
Elena Yu. Andryukhina, Liliya K. Shpigun
core   +1 more source

Sequential versus Combined Glaucoma and Cataract Procedures in Siriraj Hospital

open access: yesSiriraj Medical Journal, 2006
Objective: To compare the efficacy of intraocular pressure (IOP) control after combined cataract and trabeculectomy with sequential cataract surgery after trabeculectomy, both with and without antimetabolites.
Darin Sakiyalak   +2 more
doaj  

Late onset of sequential multifocal bleb leaks after filtration surgery with antimetabolites (5-fluorouracil and mitomycin C)

open access: yes, 1996
Purpose. Antimetabolites increase the success of filtration surgery but also increase the post-operative complications. We describe the late onset of sequential multifocal bleb leaks as a previously unreported postoperative complication after filtering ...
Belyea, D. A.   +4 more
core  

A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2018
Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation.
Harikesh Sharma, Ajay Mallick
doaj  

Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas

open access: yesIndian Journal of Ophthalmology, 1997
Thirty-three eyes of 33 patients were prospectively evaluated to study the short term efficacy, safety, and overall surgical outcome of initial trabeculectomy for primary glaucomas with adjunctive intraoperative or postoperative 5-Fluorouracil (5-FU) use.
Lamba P, Pandey P, Raina U, Krishna V
doaj  

Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate

open access: yes, 2008
BACKGROUND AND OBJECTIVE: Through interruption of maintenance treatment with 6-mercaptopurine (6MP), toxicity after high-dose methotrexate (HDMTX) may compromise the efficiency of the treatment of children with acute lymphocytic leukaemia (ALL).
Niekerk, P.B. van Kooten   +2 more
core   +1 more source

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