Results 111 to 120 of about 17,951 (205)

Antimetabolites in the treatment of arthritis:current status of the use of antimetabolites

Nucleosides, nucleotides & nucleic acids, 2004
Rheumatoid arthritis (RA) is an autoimmune disease characterized by a chronic inflammation of the synovial joints and infiltration of blood-derived cells. In daily practice rheumatologists use the antimetabolites methotrexate (MTX) and leflunomide for the treatment of patients with rheumatoid arthritis.
Dijkmans, B A C, Jansen, G
openaire   +2 more sources

Figure S4 from PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer

Figure S4. Knockout or knockdown of RIP3, but not RIP1, suppressed necroptosis induced by 5-FU and other antimetabolites.
Xinyan Lu (18098887), Lin Zhang (14956095), Yi-Jun Wang (18098881), Kaylee Ermine (14956089), Jian Yu (14956092), Xiaojun Chen (18098884), Peng Wang (18098890), Dongshi Chen (18098878), Donna Beer-Stolz (18098893)   +8 more
core   +1 more source

The proposed antiplasmodial mechanisms of action of various pantothenate analogues in Plasmodium falciparum.

, 2018
PanOH and CJ-15,801 (orange) are phosphorylated by PfPanK and their phosphorylated forms accumulate (indicated by the bigger font) and then competitively inhibit PfPPCS. The step mediated by PfPPCS has been hypothesised to be a pathway flux control point
Ghizal Siddiqui (5052374), Kevin J. Saliba (284698), Alexander G. Maier (3955484), Leanne Barnard (2902149), Christina Spry (284689), Erick Strauss (284696), Annabelle Hoegl (1632676), Erick T. Tjhin (5052377), Rodolfo Marquez (2053600), Anna E. Sexton (3804184), Alan L. Sewell (2222434), Darren J. Creek (167726), Karine Auclair (1494094), Vanessa M. Howieson (5052380)   +13 more
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Sequential versus Combined Glaucoma and Cataract Procedures in Siriraj Hospital

Siriraj Medical Journal, 2006
Objective: To compare the efficacy of intraocular pressure (IOP) control after combined cataract and trabeculectomy with sequential cataract surgery after trabeculectomy, both with and without antimetabolites.
Darin Sakiyalak, Teeravee Hongyok, Naris Kitnarong   +2 more
doaj  

Figure S3 from PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer

Figure S3. 5-FU and other antimetabolites induced necroptosis in p53-WT CRC cells expressing RIP3.
Xinyan Lu (18098887), Lin Zhang (14956095), Yi-Jun Wang (18098881), Kaylee Ermine (14956089), Jian Yu (14956092), Xiaojun Chen (18098884), Peng Wang (18098890), Dongshi Chen (18098878), Donna Beer-Stolz (18098893)   +8 more
core   +1 more source

Figure S5 from PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer

Figure S5. PUMA was induced by p53 and required for necroptosis induction in LoVo cells treated with antimetabolites.
Xinyan Lu (18098887), Lin Zhang (14956095), Yi-Jun Wang (18098881), Kaylee Ermine (14956089), Jian Yu (14956092), Xiaojun Chen (18098884), Peng Wang (18098890), Dongshi Chen (18098878), Donna Beer-Stolz (18098893)   +8 more
core   +1 more source

A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy

Bengal Journal of Otolaryngology and Head Neck Surgery, 2018
Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation.
Harikesh Sharma, Ajay Mallick
doaj  

Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas

Indian Journal of Ophthalmology, 1997
Thirty-three eyes of 33 patients were prospectively evaluated to study the short term efficacy, safety, and overall surgical outcome of initial trabeculectomy for primary glaucomas with adjunctive intraoperative or postoperative 5-Fluorouracil (5-FU) use.
Lamba P, Pandey P, Raina U, Krishna V
doaj  

Anthracycline and antimetabolite, trigger distinct resistance mechanisms in TP53^mut AML. [PDF]

Cell Death Discov
Raghuwanshi S, Gartel AL.
europepmc   +1 more source

A rational approach to chemotherapy : the history of antimetabolites (1935-1955)

, 2016
En 1940, le biochimiste anglais Donald Woods propose une explication du mode d'action des nouveaux sulfamides antibactériens : l'inhibition compétitive. Son collègue Paul Fildes fonde sur cette base une nouvelle approche de la chimiothérapie, revendiquée
Serviant-Fine, Thibaut
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