Results 161 to 170 of about 17,951 (205)
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Cancer chemotherapy and biological response modifiers, 1990
The mechanisms of action of MTX and 5-FU have been further elucidated. Such studies will be important for the design of drug combinations and for the development of novel antifolate and fluoropyrimidine analogs. A greater understanding of MTX and ara-C transport and drug levels required to optimize transport may also aid in these endeavors ...
C J, Allegra +5 more
+7 more sources
The mechanisms of action of MTX and 5-FU have been further elucidated. Such studies will be important for the design of drug combinations and for the development of novel antifolate and fluoropyrimidine analogs. A greater understanding of MTX and ara-C transport and drug levels required to optimize transport may also aid in these endeavors ...
C J, Allegra +5 more
+7 more sources
Bulletin du cancer, 2012
Antimetabolites are cytotoxic agents, which have been developed for more than 50 years. Which cancer patient did not receive or will not receive 5-fluorouracil or methotrexate during the evolution his or her disease? Antimetabolites are defined as interfering with the synthesis of the DNA constituents; they are structural analogues, either of purine ...
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Antimetabolites are cytotoxic agents, which have been developed for more than 50 years. Which cancer patient did not receive or will not receive 5-fluorouracil or methotrexate during the evolution his or her disease? Antimetabolites are defined as interfering with the synthesis of the DNA constituents; they are structural analogues, either of purine ...
openaire +3 more sources
Baillière's Clinical Haematology, 1991
R L, Capizzi, J C, White, D J, Fernandes
openaire +4 more sources
R L, Capizzi, J C, White, D J, Fernandes
openaire +4 more sources
Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs
Current Medicinal Chemistry, 2023Ramon Eritja, Anna Clua, Ana Aviñó
exaly