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Antimicrobial Resistance: A Growing Serious Threat for Global Public Health
Antibiotics are among the most important discoveries of the 20th century, having saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from ...
Md Abdus Salam +6 more
semanticscholar +1 more source
We are living in a time of enormous risk. Years of antibiotic overuse and misuse has contributed to a global threat, where an increase in antibiotic resistant bacteria are contributing to approximately 700,000 deaths per year. International institutions such as the World Health Organization (WHO) and the UK government are calling for new antibiotics ...
Birnbaum, H, Roughley, M, D'Sa, R
openaire +2 more sources
The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents. Here we review the history and new development of antimicrobial peptides (AMPs), a growing class of natural and synthetic
Ali Adem Bahar, Dacheng Ren
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Antimicrobial Chemokines [PDF]
Chemokines are best known for their classic leukocyte chemotactic activity, which is critical for directing the immune response to sites of infection and injury. However, recent studies have suggested that at least some chemokines may also interfere with infectious agents directly.
Yung, Sunny C., Murphy, Philip M.
openaire +3 more sources
Antimicrobial Resistance (AMR)
Antimicrobial resistance (AMR) has now emerged as a chronic public health problem globally, with the forecast of 10 million deaths per year globally by 2050.
Kashem Tang, B. Millar, J. Moore
semanticscholar +1 more source
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all multicellular organisms. These proteins can have broad activity to directly kill bacteria, yeasts, fungi, viruses and even cancer cells.
Zhang, Ling-juan, Gallo, Richard L.
openaire +2 more sources
Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific metal may be essential for survival yet toxic in certain forms and concentrations.
Angelo Frei +4 more
semanticscholar +1 more source
Antimicrobial peptides: agents of border protection for companion animals. [PDF]
Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K +2 more
core +1 more source
Global trends in antimicrobial use in food-producing animals: 2020 to 2030
Use of antimicrobials in farming has enabled the growth of intensive animal production and helped in meeting the global increase in demand for animal protein.
Ranya Mulchandani +3 more
semanticscholar +1 more source
Antimicrobial resistance of clinical isolates of Klebsiella pneumoniae and Escherichia coli in Russian hospitals: results of a multicenter epidemiological study [PDF]
Objective. To study the prevalence and mechanisms of antibiotic resistance, including carbapenemase production, in clinical isolates of Klebsiella pneumoniae and Escherichia coli isolated in different regions of Russia as part of the sentinel ...
Edelstein M.V. +12 more
doaj +1 more source

