Results 41 to 50 of about 90,280 (287)

Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives

Scientific Reports, 2019
In the search for potential mechanisms underlying the remarkable resistance of healthy skin against infection by soil bacteria like Pseudomonas (P.) aeruginosa we identified fragments of the intrinsically disordered protein hornerin as potent ...
Ties Latendorf, U. Gerstel, Zhihong Wu, J. Bartels, Alexander Becker, A. Tholey, J. Schröder   +6 more
semanticscholar   +1 more source

Binding of cationic analogues of α-MSH to lipopolysaccharide and disruption of the cytoplasmic membranes caused bactericidal action against Escherichia coli

Scientific Reports, 2022
In earlier reports, we have shown the antimicrobial activity of a host neuropeptide, alpha-melanocyte stimulating hormone (α-MSH) and its cationic analogues against Staphylococcus aureus.
Kanchan Tiwari, Madhuri Singh, Prince Kumar, Kasturi Mukhopadhyay   +3 more
doaj   +1 more source

Microbial Cationic Peptides as a Natural Defense Mechanism against Insect Antimicrobial Peptides

ACS Chemical Biology, 2021
Bacteria produce a plethora of specialized metabolites (SM), with the ecological function of most of them not known. A major group of SM are peptides derived from nonribosomal peptide synthetases (NRPS). In entomopathogenic bacteria of the genus Xenorhabdus, PAX (peptide-antimicrobial-Xenorhabdus) were described as NRPS-derived lipopeptides, which show
Tien Duy Vo, Christoph Spahn, Mike Heilemann, Helge B. Bode   +3 more
openaire   +4 more sources

Short, Synthetic Cationic Peptides Have Antibacterial Activity against Mycobacterium smegmatis by Forming Pores in Membrane and Synergizing with Antibiotics

Antibiotics, 2015
Multicellular organisms are constantly exposed to a multitude of pathogenic microbes. Infection is inhibited in vivo by the innate and adaptive immune system. Mycobacterium species have emerged that are resistant to most antibiotics.
Kajal Gupta, Sameer Singh, Monique L. van Hoek   +2 more
doaj   +1 more source

Bactericidal activity of amphipathic cationic antimicrobial peptides involves altering the membrane fluidity when interacting with the phospholipid bilayer.

Biochimica et Biophysica Acta - Biomembranes, 2018
BACKGROUND Amphipathic cationic antimicrobial peptides (AMPs) TC19 and TC84, derived from the major AMPs of human blood platelets, thrombocidins, and Bactericidal Peptide 2 (BP2), a synthetic designer peptide showed to perturb the membrane of Bacillus ...
S. Omardien, J. Drijfhout, F. Vaz, Michaela Wenzel, L. Hamoen, S. Zaat, S. Brul   +6 more
semanticscholar   +1 more source

Antimicrobials, stress and mutagenesis.

PLoS Pathogens, 2014
Cationic antimicrobial peptides are ancient and ubiquitous immune effectors that multicellular organisms use to kill and police microbes whereas antibiotics are mostly employed by microorganisms.
Alexandro Rodríguez-Rojas, Olga Makarova, Jens Rolff   +2 more
doaj   +1 more source

Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities

Molecules, 2020
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic molecules produced by prokaryotic and eukaryotic organisms that play a key role in the innate immune defense against viruses, bacteria and fungi.
Anna Lucia Tornesello, Antonella Borrelli, Luigi Buonaguro, Franco Maria Buonaguro, Maria Lina Tornesello   +4 more
doaj   +1 more source

Antimicrobial Peptides: An Update on Classifications and Databases

International Journal of Molecular Sciences, 2021
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an indispensable component of host defenses. They consist of predominantly short cationic peptides with a wide variety of structures and targets.
Ahmer Bin Hafeez, Xukai Jiang, P. Bergen, Yan Zhu   +3 more
semanticscholar   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Improving the Activity of Trp-Rich Antimicrobial Peptides by Arg/Lys Substitutions and Changing the Length of Cationic Residues

Biomolecules, 2018
Antimicrobial peptides (AMPs) constitute a promising alternative for the development of new antibiotics that could potentially counteract the growing number of antibiotic-resistant bacteria.
M. Arias, Kathlyn B. Piga, M. E. Hyndman, H. Vogel   +3 more
semanticscholar   +1 more source