Results 191 to 200 of about 216,614 (305)

How Did COVID-19 Impact the Antimicrobial Consumption and Bacterial Resistance Profiles in Brazil? [PDF]

open access: yesAntibiotics (Basel), 2023
Massarine NCM   +7 more
europepmc   +1 more source

Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy

open access: yesAdvanced Science, EarlyView.
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen   +14 more
wiley   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

open access: yesAdvanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang   +7 more
wiley   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

open access: yesAdvanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng   +11 more
wiley   +1 more source

Comparison of Spectrum Coverage Score-based Antimicrobial Consumption in Acute Care Hospitals Over Eight Years: A Multicentric Study. [PDF]

open access: yesOpen Forum Infect Dis
Honda H   +11 more
europepmc   +1 more source

Analysis of European Surveillance of Antimicrobial Consumption/European Antimicrobial Resistance Surveillance Network Data from 29 EEA Countries for Spatiotemporal Associations Between Antimicrobial Consumption and Resistance—Implications for Antimicrobial Stewardship?

open access: yes
Background Antimicrobial resistance is one of the foremost global health concerns of today and could offset much of the progress accrued in healthcare over the last century. Excessive antibiotic use accelerates this problem but it is recognised that specific agents differ in their capacity to promote resistance, a concept recently promoted by the World
openaire   +1 more source

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