Results 21 to 30 of about 119,446 (259)

Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids

open access: yesScientific Reports, 2020
Rapid infection diagnosis is critical to improving patient treatment and outcome. Recent studies have shown microbial lipids to be sensitive and selective biomarkers for identifying bacterial and fungal species and antimicrobial resistance.
Matthew Sorensen   +9 more
doaj   +1 more source

Effect of CM15 on Supported Lipid Bilayer Probed by Atomic Force Microscopy

open access: yesMembranes, 2023
Antimicrobial peptides are key components of the immune system. These peptides affect the membrane in various ways; some form nano-sized pores, while others only produce minor defects.
Olivia D. Walsh   +2 more
doaj   +1 more source

Antimicrobial Peptide-Lipid Binding Interactions and Binding Selectivity [PDF]

open access: yesBiophysical Journal, 2007
Surface pressure measurements, external reflection-Fourier transform infrared spectroscopy, and neutron reflectivity have been used to investigate the lipid-binding behavior of three antimicrobial peptides: melittin, magainin II, and cecropin P1. As expected, all three cationic peptides were shown to interact more strongly with the anionic lipid, 1,2 ...
Lad, Mitaben D.   +5 more
openaire   +2 more sources

Antimicrobial Lipids from Plants and Marine Organisms: An Overview of the Current State-of-the-Art and Future Prospects

open access: yesAntibiotics, 2020
In the actual post-antibiotic era, novel ways of rethinking antimicrobial research approaches are more urgent than ever. Natural compounds with antimicrobial activity such as fatty acids and monoacylglycerols have been investigated for decades ...
Eliana Alves   +5 more
doaj   +1 more source

Antimicrobial Tear Lipids in the Ocular Surface Defense

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
The concept of antimicrobial lipids as effectors of innate host defense is an emerging field. There is limited knowledge on the antimicrobial role of lipids in the ocular environment. Tears act as first line of defense to protect the ocular surface from infections.
openaire   +4 more sources

Depleting cationic lipids involved in antimicrobial resistance drives adaptive lipid remodeling inEnterococcus faecalis

open access: yesmBio, 2022
AbstractThe bacterial cell membrane is an interface for cell envelope synthesis, protein secretion, virulence factor assembly and a target for host cationic antimicrobial peptides (CAMPs). To resist CAMP killing, several Gram-positive pathogens encode the multiple peptide resistance factor (MprF) enzyme that covalently attaches cationic amino acids to ...
Rafi Rashid   +10 more
openaire   +5 more sources

Study of the Physicochemical and Biological Properties of the Lipid Complex of Marine Microalgae Isolated from the Coastal Areas of the Eastern Water Area of the Baltic Sea

open access: yesMolecules, 2022
The Baltic Sea algae species composition includes marine euryhaline, freshwater euryhaline, and true brackish water forms. This study aimed to isolate a lipid–pigment complex from microalgae of the Baltic Sea (Kaliningrad region) and investigate its ...
Vyacheslav Dolganyuk   +7 more
doaj   +1 more source

Trehalose Lipid Biosurfactant Reduces Adhesion of Microbial Pathogens to Polystyrene and Silicone Surfaces: An Experimental and Computational Approach

open access: yesFrontiers in Microbiology, 2018
Rhodococcus fascians BD8, isolated from Arctic soil, was found to produce biosurfactant when grown on n-hexadecane as the sole carbon source. The glycolipid product was identified as the trehalose lipid with a molecular mass of 848 g mol−1.
Tomasz Janek   +3 more
doaj   +1 more source

Effects of Calcium Ions on the Antimicrobial Activity of Gramicidin A

open access: yesBiomolecules, 2022
Gramicidin A (gA) is a linear antimicrobial peptide that can form a channel and specifically conduct monovalent cations such as H+ across the lipid membrane.
Shang-Ting Fang   +5 more
doaj   +1 more source

Lipid Clustering by Antimicrobial Polymers and Lectins [PDF]

open access: yesBiophysical Journal, 2017
The current urge to understand the role of lipids in defense against pathogens is driven by two strategies: killing pathogens and protecting the cell from infection. Antimicrobial peptides and antimicrobial polymers offer a promising alternative to classical antibiotics through their action on membrane integrity.
Anja Stulz   +4 more
openaire   +1 more source

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