Mechanistic Evaluation of Antimicrobial Lipid Interactions with Tethered Lipid Bilayers by Electrochemical Impedance Spectroscopy [PDF]
Sensors, 2022 There is extensive interest in developing real-time biosensing strategies to characterize the membrane-disruptive properties of antimicrobial lipids and surfactants.
Sue Woon Tan +3 more
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Lipid-Based Nanostructures for the Delivery of Natural Antimicrobials [PDF]
Molecules, 2021 Encapsulation can be a suitable strategy to protect natural antimicrobial substances against some harsh conditions of processing and storage and to provide efficient formulations for antimicrobial delivery. Lipid-based nanostructures, including liposomes,
Cristian Mauricio Barreto Pinilla +2 more
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Synergistic Membrane Disruption of E. coli Tethered Lipid Bilayers by Antimicrobial Lipid Mixtures [PDF]
BiomimeticsBiomimetic lipid platforms provide versatile tools for mimicking various types of biological membranes and enable investigation of how industrially important amphiphiles (e.g., permeation enhancers and surfactants) interact with different membrane ...
Tun Naw Sut +2 more
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Unraveling How Antimicrobial Lipid Mixtures Disrupt Virus-Mimicking Lipid Vesicles: A QCM-D Study [PDF]
BiomimeticsSingle-chain lipid amphiphiles such as fatty acids and monoglycerides are promising antimicrobial alternatives to replace industrial surfactants for membrane-enveloped pathogen inhibition.
Suji Moon +3 more
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Development of a water-dispersible antimicrobial lipid mixture to inhibit African swine fever virus and other enveloped viruses [PDF]
Virus ResearchMedium-chain antimicrobial lipids are promising antiviral agents to inhibit membrane-enveloped viruses such as African swine fever virus (ASFV) and influenza A virus (IAV) in livestock applications.
Joshua A. Jackman +6 more
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Analysis of pathogen distribution and association with lipid levels in patients with diabetic foot [PDF]
Frontiers in MedicineBackgroundDiabetic foot infection (DFI) is a severe complication of diabetes, and dyslipidemia is common in affected patients. However, the relationship between lipid profiles, pathogen distribution, and antimicrobial resistance in DFI remains unclear ...
Yan Chen, Weihong Chen, Yinxia Zhuo
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Lipid selectivity in novel antimicrobial peptides: Implication on antimicrobial and hemolytic activity [PDF]
Colloids and Surfaces B: Biointerfaces, 2017 Antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses. For an AMP to be considered as a therapeutic option, it must have not only potent antibacterial properties but also low hemolytic and cytotoxic activities [1].
Paulo C Maffia +2 more
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Bacterial cell fate under stress: lipid remodeling and antimicrobial peptide attack [PDF]
npj Antimicrobials and ResistanceDynamic changes in lipid membrane composition are a common response to stress, often involving shifts in key lipid molecules. Phosphatidic acid (PA), a central precursor in lipid biosynthesis, accumulates when anionic phospholipid synthesis is blocked ...
Djenana Vejzovic +5 more
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Antimicrobial peptide activity is anticorrelated with lipid a leaflet affinity.
PLoS ONE, 2020 The activity of antimicrobial peptides (AMPs) has significant bacterial species bias, the mechanisms of which are not fully understood. We employed single-molecule tracking to measure the affinity of three different AMPs to hybrid supported bilayers ...
Nathaniel Nelson +3 more
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PharmaceuticsThe opportunistic bacteria growing in biofilms play a decisive role in the pathogenesis of chronic infectious diseases. Biofilm-dwelling bacteria behave differently than planktonic bacteria and are likely to increase resistance and tolerance to ...
Anam Ahsan +6 more
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