Results 71 to 80 of about 264,067 (270)

Targeted antimicrobial therapy against Streptococcus mutans establishes protective non-cariogenic oral biofilms and reduces subsequent infection. [PDF]

, 2010
AimDental biofilms are complex communities composed largely of harmless bacteria. Certain pathogenic species including Streptococcus mutans (S. mutans) can become predominant when host factors such as dietary sucrose intake imbalance the biofilm ecology.
Anderson, Maxwell, Eckert, Randal, Guo, Li-hong, He, Jian, Li, Li-na, Lux, Renate, Shi, Wen-yuan, Yarbrough, Daniel   +7 more
core   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Effects of Cations and PH on Antimicrobial Activity of Thanatin and s-Thanatin against _Escherichia coli_ ATCC25922 and _B. subtilis_ ATCC 21332 [PDF]

, 2008
Thanatin and s-thanatin were insect antimicrobial peptides which have shown potent antimicrobial activities on a variety of microbes. In order to investigate the effect of cations and pH on the activity of these peptides against Gram-negative bacteria ...
Guoqiu Wu, Hui Li, Jiaxuan Ding, Linxian Li, Rui Zhao, Xiaobo Fan, Zilong Shen   +6 more
core   +1 more source

The role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10 [PDF]

, 2014
Phosphopantetheinyltransferase (PPTase) enzymes fulfil essential roles in primary and secondary metabolism in prokaryotes, archaea and eukaryotes. PPTase enzymes catalyse the essential modification of the carrier protein domain of fatty acid synthases ...
Amy J. Gerc, Elovson, Flyg, Herrero, Matsuyama, Nicola R. Stanley-Wall, Perego, Persmark, Sarah J. Coulthurst, Seyedsayamdost   +9 more
core   +4 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi

Biomolecules, 2019
Amphibians are a natural source of abundant antimicrobial peptides and thus have been widely investigated for isolation of such biomolecules. Many new antimicrobial peptide families have been discovered from amphibians.
Bin Li, Peng Lyu, Shuping Xie, Haixin Qin, Wenyuan Pu, Houxi Xu, Tianbao Chen, Chris Shaw, Lilin Ge, Hang Fai Kwok   +9 more
doaj   +1 more source

Identification of a Novel Antimicrobial Peptide From the Ancient Marine Arthropod Chinese Horseshoe Crab, Tachypleus tridentatus

Frontiers in Immunology, 2022
Humoral immunity is the first line of defense in the invertebrate immune system, and antimicrobial peptides play an important role in this biological process.
Wei-Feng Wang, Xiao-Yong Xie, Yan Huang, Yin-Kang Li, Hong Liu, Xiu-Li Chen, Huan-Ling Wang   +6 more
doaj   +1 more source

Controlled functional expression of the bacteriocins pediocin PA-1 and bactofencin A in Escherichia coli [PDF]

, 2017
peer-reviewedThe bacteriocins bactofencin A (class IId) and pediocin PA-1 (class IIa) are encoded by operons with a similarly clustered gene organization including a structural peptide, an immunity protein, an ABC transporter and accessory bacteriocin ...
Cotter, Paul D., Hill, Colin, Mesa-Pereira, Beatriz, O’Connor, Paula M., Rea, Mary, Ross, R Paul   +5 more
core   +3 more sources

Reconfigurable Magnetic Soft Microrobot for Acoustically Triggered Targeted Bacterial Sterilization

Advanced Functional Materials, EarlyView.
Reconfigurable magnetic soft microrobots integrate in situ‐grown piezoelectric zinc oxide nanorods that produce reactive oxygen species upon acoustic excitation. Combining magnetically guided transport with thermally induced planar reconfiguration, the microrobots achieve targeted delivery and enhanced bacterial sterilization through efficient on ...
Quan Gao, Fan Li, Jiajie Gao, Elric Zhang, Yingdong Su, Ni Qin, Hao Ye, Josep Puigmartí, Giuseppe Cantarella, Simone Schuerle, Jiang Wu, Bradley J. Nelson, Salvador Pané   +12 more
wiley   +1 more source

Peptide Stapling Applied to Antimicrobial Peptides

Antibiotics, 2023
Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço, Thuanny Borba Rios, Állan Pires da Silva, Octávio Luiz Franco, Marcelo Henrique Soller Ramada   +4 more
openaire   +3 more sources