Results 71 to 80 of about 1,018,087 (252)

Antimicrobial peptide coating of TiO2 nanoparticles for boosted antimicrobial effects [PDF]

This study explores coating of photocatalytic nanoparticles with antimicrobial peptides (AMPs) for boosted antimicrobial effects, and how such effects depend on AMP properties.
Federica , Sebastiani, Samantha , Micciulla, Sebastian , Köhler, Martin, Malmsten, Lucrezia, Caselli, Tanja , Traini, Maximilian W. A. , Skoda, Emilie Marie , Nielsen, Ragna , Guldsmed Diedrichsen   +8 more
core   +1 more source

LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi

Biomolecules, 2019
Amphibians are a natural source of abundant antimicrobial peptides and thus have been widely investigated for isolation of such biomolecules. Many new antimicrobial peptide families have been discovered from amphibians.
Bin Li, Peng Lyu, Shuping Xie, Haixin Qin, Wenyuan Pu, Houxi Xu, Tianbao Chen, Chris Shaw, Lilin Ge, Hang Fai Kwok   +9 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

A novel chimeric peptide with antimicrobial activity

, 2015
Beta-lactamase-mediated bacterial drug resistance exacerbates the prognosis of infectious diseases, which are sometimes treated with co-administration of beta-lactam type antibiotics and beta-lactamase inhibitors.
SARIYAR AKBULUT, BERNA
core   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

CL-ACP: a parallel combination of CNN and LSTM anticancer peptide recognition model

BMC Bioinformatics, 2021
Background Anticancer peptides are defence substances with innate immune functions that can selectively act on cancer cells without harming normal cells and many studies have been conducted to identify anticancer peptides. In this paper, we introduce the
Huiqing Wang, Jian Zhao, Hong Zhao, Haolin Li, Juan Wang   +4 more
doaj   +1 more source

Peptide-cotton textiles with manifold antibacterial properties

, 2022
The development of antimicrobial materials recently have gained increased interest, especially for the development of medical devices as a practical way to prevent bacterial infections.
Marco Scocchi, Barbara Biondi, Cristina Peggion, Mario Mardirossian   +3 more
core  

The Putative Role of Human Peritoneal Adipocytes in the Fight against Bacteria: Synthesis of the Antimicrobial Active Peptide DEFA1-3 [PDF]

, 2010
Background: Spontaneous peritonitis is a rather rare event, even in peritoneal dialysis (PD). As defensins are natural antimicrobial peptides, we hypothesized that adipocytes as the major constituents of the omentum could play an important role in ...
Paslakis, Georgios, Schmid, Holger, Schloendorff, Detlef, Keuneke, Christian, Schroppel, Bernd, Groene, Hermann-Josef   +5 more
core   +1 more source

The Assessment of Vitamin D, Antimicrobial Peptides and Procalcitonin in Bronchiectasis [PDF]

, 2014
My research investigated the distribution of antimicrobial peptides (cathelicidin and β-defensin 2), vitamin D and the inflammatory marker procalcitonin, between systemic and localised respiratory levels in stable bronchiectasis patients.
Gartner, Sarah Nicole
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