Results 181 to 190 of about 138,424 (279)

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

In silico-designed antimicrobial peptide targeting MRSA and E. coli with antibacterial and antibiofilm actions

Hafsa Madni, Hana A. Mohamed, Hana A. Abdelrahman, Carlos André dos Santos-Silva, Ana Maria Benko‐Iseppon, Zenaba Khatir, Nahla O. Eltai, Nura A. Mohamed, Sérgio Crovella   +8 more
openalex   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Hijacking the Electron Train: Menaquinone-Binding Antimicrobial Peptides. [PDF]

Chembiochem
Matheson EJ, Cochrane SA.
europepmc   +1 more source

Antimicrobial efficacy of a synthetic antimicrobial peptide against mammary pathogenic Escherichia coli (MPEC)

KRP Niranjana, M. Raja
openalex   +1 more source

Dysbiosis in Inflammatory Bowel Disease: A Link With Antimicrobial Peptides Secretion?

, 2011
Sylvie Rajca, Henri Duboc, Harry Sokol, L. Humbert, Virginie Grondin, Ginette Thomas, Laurent Beaugerie, Philippe Langella, Muriel Thomas, Laurent Beaugerie, Jacques Cosnes, J. Masliah, Dominique Rainteau, Philippe Seksik   +13 more
openalex   +1 more source

Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells [PDF]

, 2008
H. Suttmann, Margitta Retz, Friedrich Paulsen, Jürgen Harder, Ulrike Zwergel, Jörn Kamradt, Bernd Wullich, Gerhard Unteregger, Michael Stöckle, Jan Lehmann   +9 more
openalex   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Antimicrobial peptides: natural templates for next-generation therapeutics against antimicrobial resistance. [PDF]

Front Cell Infect Microbiol
Ngashangva N, Huidrom S, Devi IS.
europepmc   +1 more source

Antimicrobial and Membrane Disrupting Activities of a Peptide Derived from the Human Cathelicidin Antimicrobial Peptide LL37 [PDF]

, 2010
Sathiah Thennarasu, Anmin Tan, Rajesh Penumatchu, Charles E. Shelburne, Deborah Heyl, Ayyalusamy Ramamoorthy   +5 more
openalex   +1 more source