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Detection of antimicrobial peptides from fecal samples of FMT donors using deep learning. [PDF]
Front Vet SciWei S +7 more
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Antimicrobial Peptides of the Cathelicidin Family: Focus on LL-37 and Its Modifications. [PDF]
Int J Mol SciVoronko OE +4 more
europepmc +1 more source
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Surgical Infections, 2018
Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections. Antimicrobial peptides (AMPs) are naturally occurring compounds produced by all prokaryotic and eukaryotic cells that have potential as an alternative to ...
Srinjoy Chakraborti, Sanjay Ram
openaire +3 more sources
Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections. Antimicrobial peptides (AMPs) are naturally occurring compounds produced by all prokaryotic and eukaryotic cells that have potential as an alternative to ...
Srinjoy Chakraborti, Sanjay Ram
openaire +3 more sources
Journal of the American Academy of Dermatology, 2005
Antimicrobial peptides (AMPs) are small molecular weight proteins with broad spectrum antimicrobial activity against bacteria, viruses, and fungi. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid ...
Arash, Izadpanah, Richard L, Gallo
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Antimicrobial peptides (AMPs) are small molecular weight proteins with broad spectrum antimicrobial activity against bacteria, viruses, and fungi. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid ...
Arash, Izadpanah, Richard L, Gallo
openaire +3 more sources
Branched antimicrobial peptides
Russian Journal of Bioorganic Chemistry, 2007Branched peptides E(RLAR)2, E[E(RLAR)2]2, E(KLAR)2, and E[E(KLAR)2]2 were synthesized on the basis of tetrapeptides RLAR and KLAR and glutamic acid bis(pentafluorophenyl) ester. Their minimal antimicrobial concentrations were shown to decrease along with increase in branching, achieving 12 microM for Escherichia coli cells, which is comparable to ...
A Iu, Khrushchev +3 more
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Recent Patents on Anti-Infective Drug Discovery, 2018
After the era of serendipitous discovery of penicillin and outburst in the discovery and development of highly efficient antibiotics, a surge in resistance against the target specific drugs was observed, primarily due to a combination of selective pressure of antibiotics use and spontaneous mutations.
Komal, Sharma +3 more
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After the era of serendipitous discovery of penicillin and outburst in the discovery and development of highly efficient antibiotics, a surge in resistance against the target specific drugs was observed, primarily due to a combination of selective pressure of antibiotics use and spontaneous mutations.
Komal, Sharma +3 more
openaire +2 more sources
Antimicrobial Peptides: Amphibian Host Defense Peptides
Current Medicinal Chemistry, 2019Antimicrobial Peptides (AMPs) are one of the most common components of the innate immune system that protect multicellular organisms against microbial invasion. The vast majority of AMPs are isolated from the frog skin. Anuran (frogs and toads) skin contains abundant AMPs that can be developed therapeutically.
Jiri, Patocka +4 more
openaire +2 more sources