Results 61 to 70 of about 1,118,223 (258)

Retrospective Analysis of Sensitivity Characteristics of Enterobacteriaceae: A Study Based on Specimen Types, Sex, and Age Bracket of Patients

Infection and Drug Resistance, 2023
Hainan Wen,1 Shoujun Xie,1 Yanchao Liu,1 Yueyi Liang,1 Pan Zhang,1 Xiaohui Wang,1 Jianhui Li2 1Department of Clinical Laboratory, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China; 2Department of Preventive ...
Wen H, Xie S, Liu Y, Liang Y, Zhang P, Wang X, Li J   +6 more
doaj  

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Study of Molecular Mechanism of Antibiotic susceptibility against Polymicrobial Oral infection [PDF]

, 2010
Introduction- Antibiotic to treat dental caries infection are routinely prescribed. Bacteria have increased resistance to the currently recommended antibiotics.
Deepak Dwivedi
core  

Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria [PDF]

, 2010
Background: Traditional antibiotics are increasingly suffering from the emergence of multidrug resistance amongst pathogenic bacteria leading to a range of novel approaches to control microbial infections being investigated as potential alternative ...
Han Haley, Jacques Vervoort, Alexandre M. J. J. Bonvin, George P Tegos, Lewis Kim, Panagiotis L. Kastritis, Vervoort, J., NMR Spectroscopy, Michael R. Hamblin, Kastritis, P., Vervoort Jacques, Exarchou, Vassiliki, Vervoort, Jacques, Bonvin, A.M., Kastritis Panagiotis L., Hamblin, Michael, Tegos, George, Tegos, George P., Lewis, K., Kim Lewis, George P. Tegos, Bonvin, Alexandre M. J. J., Panagiotis L Kastritis, Bonvin Alexandre M. J. J., Sub NMR Spectroscopy, Han, H., Tegos, G.P., Alexandre M J J Bonvin, Fiamegos Yiannis C., Fiamegos, Y.C., Yiannis C Fiamegos, Kastritis, P.L., Hamblin, Michael R., Exarchou Vassiliki, Lewis, Kim, Exarchou, V., Han, Haley, Hamblin Michael R., Tegos George P., Michael R Hamblin, Fiamegos, Yiannis C., Haley Han, Yiannis C. Fiamegos, Kastritis, Panagiotis L., Vassiliki Exarchou, Bonvin, A.M.J.J., Hamblin, M.R., Vervoort, J.J.M.   +47 more
core   +3 more sources

Sputum antimicrobial susceptibility patterns and clinical outcomes among adult Aboriginal Australians with bronchiectasis

Therapeutic Advances in Respiratory Disease
Background Prevalence of bronchiectasis among the adult Aboriginal Australians is high, estimated to be up to 19.4/1000 people, with associated higher morbidity and mortality.
Timothy Howarth, Angelou Castro, Debora Kirojan, Alison O’Connor, Stuart Campbell, Subash S. Heraganahally   +5 more
doaj   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Phenotypic and genomic characterization of Roseomonas mucosa, an opportunistic pathogen with discrepancies among antimicrobial susceptibility testing methods

Antimicrobial Agents and Chemotherapy
Roseomonas mucosa is an opportunistic bacterium found in clinical and environmental samples that primarily affects immunocompromised patients. Treatment is challenging owing to the lack of standardized susceptibility testing methods, breakpoints, and ...
Camille Cotet, Sebastien Galopin, Anne-Emeline Creach, Marwan Tenouri, Charlotte Le Pont, Nathalie Laquay, Jean-Christophe Giard, Simon Le Hello, François Gravey   +8 more
doaj   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Limited effect of patient and disease characteristics on compliance with hospital antimicrobial guidelines [PDF]

, 2005
Objective: Physicians frequently deviate from guidelines that promote prudent use of antimicrobials. We explored to what extent patient and disease characteristics were associated with compliance with guideline recommendations for three common infections.
Gans, ROB; id_orcid, Mol, PGM; id_orcid, Wieringa, Jaap E., Denig, P., Laseur, M., Haaijer-Ruskamp, F.M., Mol, Peter G. M.; id_orcid, Mol, PGM, Degener, JE, NannanPanday, P.V., Laseur, M, Denig, P; id_orcid, Wieringa, J.E., Haaijer-Ruskamp, Flora M., Mol, Peter G. M., Denig, P, NannanPanday, PV, Gans, ROB, Degener, John E., Mol, P.G.M., Gans, Rijk O. B., Gans, Rijk O. B.; id_orcid, Gans, R.O.B., Haaijer-Ruskamp, FM, Degener, J.E.   +24 more
core   +2 more sources