Results 71 to 80 of about 1,194,702 (315)

Genomic surveillance meets clinical practice: rule-based individualized treatment prediction for gonorrhoea using SensiTyper

Nature Communications
Extensively drug-resistant (XDR) Neisseria gonorrhoeae strains threaten the current empirical gonorrhoea treatment. We designed and analytically validated SensiTyper, a rule-based framework that predicts antimicrobial susceptibility from whole-genome ...
Daniel Golparian, Leonor Sánchez-Busó, Magnus Unemo   +2 more
doaj   +1 more source

Retrospective Analysis of Sensitivity Characteristics of Enterobacteriaceae: A Study Based on Specimen Types, Sex, and Age Bracket of Patients

Infection and Drug Resistance, 2023
Hainan Wen,1 Shoujun Xie,1 Yanchao Liu,1 Yueyi Liang,1 Pan Zhang,1 Xiaohui Wang,1 Jianhui Li2 1Department of Clinical Laboratory, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China; 2Department of Preventive ...
Wen H, Xie S, Liu Y, Liang Y, Zhang P, Wang X, Li J   +6 more
doaj  

Antimicrobial susceptibility of pathogens isolated from patients with complicated intra-abdominal infections at five medical centers in Taiwan that continuously participated in the Study for Monitoring Antimicrobial Resistance Trends (SMART) from 2006 to 2010

, 2014
The Study for Monitoring Antimicrobial Resistance Trends (SMART) is a worldwide surveillance program designed to longitudinally monitor the in vitro activity of antimicrobial agents against pathogens that cause intra-abdominal infections (IAIs).
Lee, Yu-Lin;Chen, Yao-Shen;Toh, Han-Siong;Huang, Chi-Chang;Liu, Yuag-Meng;Ho, Cheng-Mao;Lu, Po-Liang;Ko, Wen-Chien;Chen, Yen-Hsu;Wang, Jen-Hsien;Tang, Hung-Jen;Yu, Kwok-Woon;Liu, Yung-Ching;Chuang, Yin-Ching;Liu, Chun-Eng;Hsueh, Po-Ren, 薛博仁   +1 more
core   +1 more source

Antimicrobial susceptibility testing: Beyond S/I/R

, 2020
Antimicrobial susceptibility testing and interpretation is a critical component of antimicrobial stewardship in bovine practice, yet it remains 1 of the most poorly understood diagnostic tests in veterinary medicine.
Kreuder, Amanda J.
core   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Antimicrobial susceptibility among microorganisms causing neonatal HAIs

, 2021
This data describes the susceptibility of microorganisms towards antimicrobial therapy causing neonatal HAIs at Karnataka, South ...
RANI, U
core   +2 more sources

Sputum antimicrobial susceptibility patterns and clinical outcomes among adult Aboriginal Australians with bronchiectasis

Therapeutic Advances in Respiratory Disease
Background Prevalence of bronchiectasis among the adult Aboriginal Australians is high, estimated to be up to 19.4/1000 people, with associated higher morbidity and mortality.
Timothy Howarth, Angelou Castro, Debora Kirojan, Alison O’Connor, Stuart Campbell, Subash S. Heraganahally   +5 more
doaj   +1 more source

Antimicrobial susceptibility of the 41 CR-KP isolates to 17 common antimicrobial agents.

, 2018
Antimicrobial susceptibility of the 41 CR-KP isolates to 17 common antimicrobial agents.
Di Chen (15424), Weichun Huang (20243), Xing Wang (154377), Guifeng Xu (4984481), Xingyu Zhang (408987)   +4 more
core   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Phenotypic and genomic characterization of Roseomonas mucosa, an opportunistic pathogen with discrepancies among antimicrobial susceptibility testing methods

Antimicrobial Agents and Chemotherapy
Roseomonas mucosa is an opportunistic bacterium found in clinical and environmental samples that primarily affects immunocompromised patients. Treatment is challenging owing to the lack of standardized susceptibility testing methods, breakpoints, and ...
Camille Cotet, Sebastien Galopin, Anne-Emeline Creach, Marwan Tenouri, Charlotte Le Pont, Nathalie Laquay, Jean-Christophe Giard, Simon Le Hello, François Gravey   +8 more
doaj   +1 more source