Results 121 to 130 of about 226,602 (286)

Interdisciplinary Research-Based Learning in Organic Chemistry and Microbiology Laboratories: Synthesis and Biological Testing of Novel Penicillin Derivatives [PDF]

, 2015
Interests in the mechanism that penicillin bestows on its target protein has driven the curiosity of its binding specificity towards the methicillin resistant strain of Staphylococcus areus, and its expression of a unique penicillin binding protein that ...
Rehberger, Kyle R.
core   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Neisseria gonorrhoeae antimicrobial susceptibility testing: application of traditional agar dilution to a high-throughput 96-well microtiter assay

Microbiology Spectrum
The global rise in Neisseria gonorrhoeae infections and increasing antimicrobial resistance underscores the urgent need for accessible and efficient antimicrobial susceptibility testing methods.
Joyce E. Kuipers, Laura Seidel, Nicole E. Garnier, Cezar M. Khursigara   +3 more
doaj   +1 more source

Rapid ultrasensitive detection platform for antimicrobial susceptibility testing.

PLoS Biology, 2019
Rapid detection and phenotyping of pathogenic microbes is critical for administration of effective antibiotic therapies and for impeding the spread of antibiotic resistance.
Mehmet F Cansizoglu, Yusuf Talha Tamer, Michael Farid, Andrew Y Koh, Erdal Toprak   +4 more
doaj   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Clinical performance of the VITEK REVEAL fast antimicrobial susceptibility test within a real-world workflow for gram-negative bacteremia: comparison with QMAC-dRAST and conventional methods

Microbiology Spectrum
Fast antimicrobial susceptibility testing (AST) is essential for appropriate antimicrobial therapeutic guidance in patients with bloodstream infections, reducing the time required for optimal treatment.
Junghun Park, Hae-Sun Chung, Mihwa Kim, Yohann Bala, Geehay Hong, Miae Lee, Min-Kyung So   +6 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

Advanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju, Roshan Velluvakandy, Xianghua Wu, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Kamila Bendíčková, Jan Frič, Martin Pumera   +7 more
wiley   +1 more source