Results 11 to 20 of about 128,756 (268)
In the last couple of years, the awareness of climate change and high pollution levels have raised our sense of ecological responsibility [...]
Helena P. Felgueiras
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We are living in a time of enormous risk. Years of antibiotic overuse and misuse has contributed to a global threat, where an increase in antibiotic resistant bacteria are contributing to approximately 700,000 deaths per year. International institutions such as the World Health Organization (WHO) and the UK government are calling for new antibiotics ...
Birnbaum, H, Roughley, M, D'Sa, R
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The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents. Here we review the history and new development of antimicrobial peptides (AMPs), a growing class of natural and synthetic
Ali Adem Bahar, Dacheng Ren
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Antimicrobial Chemokines [PDF]
Chemokines are best known for their classic leukocyte chemotactic activity, which is critical for directing the immune response to sites of infection and injury. However, recent studies have suggested that at least some chemokines may also interfere with infectious agents directly.
Yung, Sunny C., Murphy, Philip M.
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Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all multicellular organisms. These proteins can have broad activity to directly kill bacteria, yeasts, fungi, viruses and even cancer cells.
Zhang, Ling-juan, Gallo, Richard L.
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Clinical decision support systems (CDSSs) are increasingly being used by clinicians to support antibiotic decision making in infection management. However, coexisting CDSSs often target different types of physicians, infectious situations, and patient ...
Claire Durand +5 more
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Antimicrobial polypeptides [PDF]
AbstractThe respiratory tract presents a large and potentially vulnerable surface to inhaled microbes. It is coated by a thin layer of secretions generated by airway epithelial cells, submucosal glands, resident and recruited phagocytes (neutrophils, eosinophils, monocytes, and macrophages) and alveolar epithelial cells, as well as substances that ...
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The O-Antigen Epitope Governs Susceptibility to Colistin in
Group D and group B Salmonella enterica serovars differ in their susceptibility to colistin with the former frequently intrinsically resistant (MIC > 2 μg/ml); however, the mechanism has not been described.
Vito Ricci +3 more
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The synergistic action of colistin, with two antibiotics active in Gram-positive bacteria but unable to kill gram negatives (linezolid and rifampicin), was investigated, since triple combinations are emerging as a tool to overtake multidrug resistance ...
Eva Armengol +3 more
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Burkholderia pseudomallei type III secreted protein BipC: role in actin modulation and translocation activities required for the bacterial intracellular lifecycle [PDF]
Melioidosis, an infection caused by the facultative intracellular pathogen Burkholderia pseudomallei, has been classified as an emerging disease with the number of patients steadily increasing at an alarming rate. B. pseudomalleipossess various virulence
Wen Tyng Kang +4 more
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