Results 11 to 20 of about 133,631 (265)
Antibiotics, 2022 Clinical decision support systems (CDSSs) are increasingly being used by clinicians to support antibiotic decision making in infection management. However, coexisting CDSSs often target different types of physicians, infectious situations, and patient ...
Claire Durand +5 more
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The O-Antigen Epitope Governs Susceptibility to Colistin in
mBio, 2020 Group D and group B Salmonella enterica serovars differ in their susceptibility to colistin with the former frequently intrinsically resistant (MIC > 2 μg/ml); however, the mechanism has not been described.
Vito Ricci +3 more
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Microorganisms, 2020 The synergistic action of colistin, with two antibiotics active in Gram-positive bacteria but unable to kill gram negatives (linezolid and rifampicin), was investigated, since triple combinations are emerging as a tool to overtake multidrug resistance ...
Eva Armengol +3 more
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Antibiotics, 2022 The objective was to compare clinical characteristics, outcomes, and economic differences in complicated urinary tract infections (cUTI) caused by extensively drug-resistant Pseudomonas aeruginosa (XDR P.
Elena Sendra +13 more
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Journal of Visual Communication in Medicine, 2020 We are living in a time of enormous risk. Years of antibiotic overuse and misuse has contributed to a global threat, where an increase in antibiotic resistant bacteria are contributing to approximately 700,000 deaths per year. International institutions such as the World Health Organization (WHO) and the UK government are calling for new antibiotics ...
Birnbaum, H, Roughley, M, D'Sa, R
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How to Measure Export via Bacterial Multidrug Resistance Efflux Pumps
mBio, 2016 Bacterial multidrug resistance (MDR) efflux pumps are an important mechanism of antibiotic resistance and are required for many pathogens to cause infection. They are also being harnessed to improve microbial biotechnological processes, including biofuel
Jessica M. A. Blair, Laura J. V. Piddock
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Free and Nanoencapsulated Tobramycin: Effects on Planktonic and Biofilm Forms of Pseudomonas
Microorganisms, 2017 Cystic fibrosis (CF) is a genetic disorder in which frequent pulmonary infections develop secondarily. One of the major pulmonary pathogens colonizing the respiratory tract of CF patients and causing chronic airway infections is Pseudomonas aeruginosa ...
Eulalia Sans-Serramitjana +5 more
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Burkholderia pseudomallei type III secreted protein BipC: role in actin modulation and translocation activities required for the bacterial intracellular lifecycle [PDF]
PeerJ, 2016 Melioidosis, an infection caused by the facultative intracellular pathogen Burkholderia pseudomallei, has been classified as an emerging disease with the number of patients steadily increasing at an alarming rate. B. pseudomalleipossess various virulence
Wen Tyng Kang +4 more
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Antimicrobial Therapy and Antimicrobial Stewardship in Sepsis
Infection & Chemotherapy, 2020 Since sepsis was first defined, sepsis management has remained challenging. To improve mortality rates for sepsis and septic shock, an accurate diagnosis and prompt administration of appropriate antibiotics are essential. The goals of antimicrobial stewardship are to achieve optimal clinical outcomes and to ensure cost-effectiveness and minimal ...
Hyeri Seok, Ji Hoon Jeon, Dae Won Park
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mBio, 2018 The rapid dissemination of antimicrobial resistance (AMR) around the globe is largely due to mobile genetic elements, such as plasmids. They confer resistance to critically important drugs, including extended-spectrum beta-lactams, carbapenems, and ...
Michelle M. C. Buckner +9 more
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