Results 21 to 30 of about 128,756 (268)
Antibiotics, 2022 The objective was to compare clinical characteristics, outcomes, and economic differences in complicated urinary tract infections (cUTI) caused by extensively drug-resistant Pseudomonas aeruginosa (XDR P.
Elena Sendra +13 more
doaj +1 more source
How to Measure Export via Bacterial Multidrug Resistance Efflux Pumps
mBio, 2016 Bacterial multidrug resistance (MDR) efflux pumps are an important mechanism of antibiotic resistance and are required for many pathogens to cause infection. They are also being harnessed to improve microbial biotechnological processes, including biofuel
Jessica M. A. Blair, Laura J. V. Piddock
doaj +1 more source
Evolution of Antimicrobial Consumption During the First Wave of COVID-19 Pandemic
Antibiotics, 2021 Background: The first wave of COVID-19 pandemic may have significantly impacted antimicrobial consumption in hospitals. The objective of this study was to assess the evolution of antimicrobial consumption during this period.
Santiago Grau +10 more
doaj +1 more source
Antimicrobial Stewardship [PDF]
Mayo Clinic Proceedings, 2011 Antimicrobial resistance is increasing; however, antimicrobial drug development is slowing. Now more than ever before, antimicrobial stewardship is of the utmost importance as a way to optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes.
Shira, Doron, Lisa E, Davidson
openaire +2 more sources
Free and Nanoencapsulated Tobramycin: Effects on Planktonic and Biofilm Forms of Pseudomonas
Microorganisms, 2017 Cystic fibrosis (CF) is a genetic disorder in which frequent pulmonary infections develop secondarily. One of the major pulmonary pathogens colonizing the respiratory tract of CF patients and causing chronic airway infections is Pseudomonas aeruginosa ...
Eulalia Sans-Serramitjana +5 more
doaj +1 more source
Pharmaceutics, 2022 The super-cationic peptide dendrimers (SCPD) family is a valuable class of antimicrobial peptide candidates for the future development of antibacterial agents against multidrug-resistant gram-negative bacteria.
Isabel Pérez-Guillén +9 more
doaj +1 more source
mBio, 2018 The rapid dissemination of antimicrobial resistance (AMR) around the globe is largely due to mobile genetic elements, such as plasmids. They confer resistance to critically important drugs, including extended-spectrum beta-lactams, carbapenems, and ...
Michelle M. C. Buckner +9 more
doaj +1 more source
Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump
mBio, 2020 Efflux is an important mechanism in Gram-negative bacteria conferring multidrug resistance. Inhibition of efflux is an encouraging strategy to restore the antibacterial activity of antibiotics.
Elizabeth M. Grimsey +10 more
doaj +1 more source
Scientific Reports, 2021 Ceftolozane/tazobactam (C/T) has emerged as a potential agent for the treatment of extensively drug-resistant (XDR) Pseudomonas aeruginosa infections.
María M. Montero +12 more
doaj +1 more source
Antibiotics, 2019 The onset and persistence of endodontic infections due to residual biofilm after chemical disinfection promotes secondary bacterial infection. Alternative methods to disinfect operated root canals are a matter of great interest.
Pablo Betancourt +4 more
doaj +1 more source