Antimitochondrial Antibodies: from Bench to Bedside. [PDF]
Clin Rev Allergy Immunol, 2022 Anti-mitochondrial antibodies (AMA) are directed against the E2 subunits of the 2-oxo acid dehydrogenase complexes (PDC-E2) and are the typical biomarkers of primary biliary cholangitis (PBC), being present in 90-95% of patients, with increasing sensitivity at increasing titers.
Colapietro F, Lleo A, Generali E.
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Antimitochondrial antibodies-positive myositis accompanied by cardiac involvement. [PDF]
BMJ Case Rep, 2017 We report a 55-year-old man who experienced proximal muscle weakness accompanied by the atrial flutter (AFL) with 1:1 conduction. Detailed examination revealed elevated antimitochondrial antibodies (AMA) and creatine kinase (CK). AFL was converted to sinus rhythm by cardioversion. He was diagnosed as AMA-positive myositis-associated AFL and was treated
Yamanaka T +3 more
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Antimitochondrial Antibodies and Primary Biliary Cholangitis in Patients with Polymyalgia Rheumatica/Giant Cell Arteritis [PDF]
Medicina, 2021 Background and Objectives: Laboratory liver abnormalities can be observed in patients affected with polymyalgia rheumatica (PMR) and/or giant cell arteritis (GCA), especially with a cholestatic pattern.
Ciro Manzo +10 more
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Annals of Hepatology, 2021 Introduction: The presence of antimitochondrial antibodies has been described as a diagnostic criterion for primary biliary cholangitis. However, no studies have been established in the South American population to describe the prevalence of these ...
Andres Gomez Aldana +5 more
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Primary Biliary Cirrhosis-Specific Antimitochondrial Antibodies in Neonatal Haemochromatosis [PDF]
Clinical and Developmental Immunology, 2013 Background and Aim. Neonatal hemochromatosis (NH) is characterised by severe liver injury and extrahepatic siderosis sparing the reticuloendothelial system.
Daniel S. Smyk +6 more
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Antimitochondrial antibody -M2 positive autoimmune hepatitis during standard of care for chronic hepatitis C. [PDF]
, 2012 The current standard of care (SoC) for chronic hepatitis C, i.e. the combination of a pegylated-interferon (PEG-IFN) with ribavirin (RBV), may activate underlying autoimmune conditions.
ALESSI, Nicola +2 more
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What does the antimitochondrial antibody mean? [PDF]
Gut, 1982 In a prospective survey positive antimitochondrial antibodies have been detected in 69/4200 (1.64%) of all sera submitted to a routine immunology laboratory. Of the 69, only nine patients had uniquivocal primary biliary cirrhosis, six others had chronic active hepatitis, 10 had abnormal liver function tests without evidence of primary biliary cirrhosis,
D R, Triger, C A, Charlton, A M, Ward
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Antimitochondrial Antibody-Positive Myositis [PDF]
The American Journal of Medicine, 2023 Kosuke Ishizuka, Yoshiyuki Ohira
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The fingerprint of antimitochondrial antibodies and the etiology of primary biliary cholangitis. [PDF]
Hepatology, 2017 Shuai Z +14 more
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A dot-immunobinding assay for antimitochondrial antibodies [PDF]
Hepatology, 1986 A dot-immunobinding assay was established for the detection of antimitochondrial antibodies. Nitrocellulose strips were coated with sonicated rat liver mitochondria and incubated in the presence of human sera. The resulting immune complexes were visualized with an enzyme-linked second antibody.
E, Penner +3 more
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