Primary biliary cholangitis (PBC) is a chronic autoimmune cholestatic liver disease characterized by T-lymphocyte-mediated damage to intrahepatic biliary epithelial cells and the presence of a specific serological marker, antimitochondrial antibodies ...
Dmitry I. Trukhan
doaj +1 more source
Autoimmune Hepatitis – Primary Biliary Cirrhosis Overlap Syndrome [PDF]
Autoimmune Hepatitis (AIH) and Primary Biliary Cirrhosis (PBC) are important immune mediated liver diseases. They are usually differentiated based on clinical, biochemical, serological and histological parameters.
INDIRA BAIRY +2 more
doaj +1 more source
PRIMARY BILIARY CHOLANGITIS DIAGNOSIS IN A SERONEGATIVE 19-YEAR-OLD WOMAN [PDF]
Primary biliary cholangitis (PBC) is an autoimmune disease that destroys small bile ducts, culminating in liver failure. It typically affects middle-aged, Caucasian women. Most cases have detectable antimitochondrial antibodies.
Sara Santos
doaj +1 more source
Evaluation of the primary biliary cholangitis-related serologic profile in a large cohort of Belgian systemic sclerosis patients [PDF]
Background: Systemic sclerosis (SSc) and primary biliary cholangitis (PBC) are autoimmune diseases that may occur concomitantly and are both strongly associated with disease-specific autoantibodies.
Bonroy, Carolien +6 more
core +1 more source
Analysis of the clinical relevance of antimitochondrial antibodies to the β- and γ-subunits of the F1F0-ATPase in patients with primary biliary cirrhosis. [PDF]
Nann D, Berg CP, Preuss BE, Klein R.
europepmc +3 more sources
Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and review of the literature. [PDF]
Invernizzi P +9 more
europepmc +3 more sources
Prevalence of Celiac Disease in Patients With Primary Biliary Cholangitis: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Celiac disease (CeD) has been linked to both autoimmunity and chronic liver disease, but most data on the link to primary biliary cholangitis (PBC) originate from small studies and have yielded conflicting results. A systematic search was performed in the databases of Medline, Embase, Cochrane and Web of Science Core Collection for studies ...
Zingone F +6 more
europepmc +2 more sources
Primary biliary cirrhosis (PBC) is an inflammatory disease or chronic liver inflammation, with slow progressive characteristic and is an unknown cholestatic liver disease and commonly happen in middle-aged women.
Irvan Nugraha +6 more
doaj +1 more source
Characterization and epitope mapping of human monoclonal antibodies to PDC-E2, the immunodominant autoantigen of primary biliary cirrhosis [PDF]
Further to define the epitopes of PDC-E2, the major autoantigen in primary biliary cirrhosis (PBC), we have developed and characterized five human monoclonal antibodies. These antibodies were derived by fusing a regional hepatic lymph node from a patient
Bassendine +49 more
core +1 more source
Mitochondrial Autoantibodies and the Role of Apoptosis in Pemphigus Vulgaris
Pemphigus vulgaris (PV) is an IgG autoantibody-mediated, potentially fatal mucocutaneous disease manifested by progressive non-healing erosions and blisters.
Dana M. Hutchison +3 more
doaj +1 more source

