Results 51 to 60 of about 4,667 (242)

Characterization of a Lipoyl Domain-Independent B-Cell Autoepitope on the Human Branched-Chain Acyltransferase in Primary Biliary Cirrhosis and Overlap Syndrome with Autoimmune Hepatitis

Clinical and Developmental Immunology, 2003
Background and aims: Antimitochondrial antibodies (AMA) which recognize pyruvate acetyltransferase (PDC-E2) represent a highly diagnostic feature of primary biliary cirrhosis (PBC).
Antal Csepregi, Petra Obermayer-Straub, Susanne Kneip, Anne Kayser, Stephanie Loges, Eleonore Schmidt, Elemér Nemesánszky, Ferenc Szalay, Michael P. Manns, Christian P. Strassburg   +9 more
doaj   +1 more source

Mixed mucus-secreting and oncocytic carcinoma of the thyroid - Pathologic, histochemical, immunohistochemical, and ultrastructural study of a case [PDF]

, 2000
We report a carcinoma that is, to the best of our knowledge, the first case of a mixed mucus-secreting and oncocytic carcinoma of the thyroid. We also describe the histochemical, immunohistochemical, and ultrastructural features of this tumor.
Erba, S, Finzi, G, La Rosa, S, Sessa, F, Uccella, S.   +4 more
core   +1 more source

IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background and Aims Immune‐mediated bile duct injury is the primary histological feature of autoimmune cholestatic liver diseases. Macrophages, the most abundant immune cell population in the liver, have been postulated to play a critical role in biliary repair. However, it is unclear whether activated macrophages interact with injured biliary
Xing Zhou, Shuyu Shao, Danning Yang, Ziyan Cheng, Toshihiro Tanaka, Patrick S. C. Leung, Koichi Tsuneyama, Aftab A. Ansari, William M. Ridgway, Pietro Invernizzi, Christopher L. Bowlus, M. Eric Gershwin, Weici Zhang   +12 more
wiley   +1 more source

T lymphocytes from patients with primary biliary cirrhosis produce reduced amounts of lymphotoxin, tumor necrosis factor and interferon-gamma upon mitogen stimulation [PDF]

, 1992
Primary biliary cirrhosis (PBC) is considered an autoimmune disease characterized by destruction of small intrahepatic bile ducts by lymphocytes. Altered functions of these lymphocytes might reflect an abnormal immune response leading to tissue damage ...
Eisenburg, Josef, Hoffmann, Robert M., Jung, Maria C., Messer, Gerald, Möller, Achim, Paumgartner, Gustav, Riethmüller, Gert, Spengler, Ulrich, Weiss, Elisabeth H., Zachoval, Reinhard   +9 more
core   +1 more source

METTL1‐Mediated N7‐Methylguanosine tRNA Modification Alleviates Cardiac Ischemia/Reperfusion Injury by Modulating Mitochondrial Energy Metabolism

MedComm, Volume 7, Issue 1, January 2026.
During cardiac I/R injury, the level of METTL1 and tRNA m7G modification increases and then leads to CMs’ mitochondrial dysfunction and aggravated cardiac injury by modulating the transcription efficiency of ATPIF1. ABSTRACT Ischemic heart disease is one of the diseases with the highest morbidity and mortality in the world. The N7‐methylguanosine (m7G)
Yue Zhang, Mingyang Leng, Ruonan Wang, Xinyuan Tang, Zhenlu Cai, Liang Wang, Xiaoqi Shao, Hongtao Diao, Qinqiang Long, Xu Li, Yingzi Wu, Yuan Jiang, Haifeng Zhang, Haihai Liang, Jiao Guo   +14 more
wiley   +1 more source

Autosplenectomy in a Patient With Autoimmune Polyglandular Syndrome Type 2 (APS‐2)

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Autoimmune glandular syndrome type 2 is a complex genetic condition where a triad of endocrinopathies is involved, namely, Addison’s disease, type 1 diabetes, and/or autoimmune thyroid disorder. The disease predisposes one to a variety of other autoimmune associations.
Luqman S. Fauzi, Airin Jyoty, Yashwin Sredharan, Manohara Kenchaiah, Osamu Isozaki   +4 more
wiley   +1 more source

Cirrosis biliar primaria: patología subdiagnosticada. Reporte de caso

Revista Médica Hondureña
Introduction: Primary biliary cirrhosis is a chronic, cholestatic, autoimmune, and progressive liver disease that pre-dominantly affects women.
Delmy Saraí Castillo Álvarez, Alejandra María Sosa, Diana Magoe Meza   +2 more
doaj   +1 more source

Lymphapheresis in organ transplantation: preliminary report. [PDF]

, 1982
Reduction of lymphoid tissue by splenectomy and/or thymectomy has been used as a part of immunosuppression in organ transplantation (4). More recently Walker (7), Johnson (2), Franksson (1) and Starzl (5,6) and their associates have shown that chronic ...
Iwaki, Y, Iwatsuki, S, Kano, T, Klintmalm, G, Krams, AK, Starzl, TE   +5 more
core  

Antibodies to Cardiolipin in Patients with Primary Biliary Cirrhosis

Canadian Journal of Gastroenterology, 1989
Antibodies to cardiolipin have been recognized in up to 65% of patients with systemic lupus erythematosus. It has been claimed that they are significantly associated with intravascular thrombosis and with obstetrical complications.
John Verrier Jones, Dianne P. Mosher, Edith Jones, C. Noel Williams, Dickran Malatjalian, Roland I. Carr, Mervat Mansour   +6 more
doaj   +1 more source

Remarkable prevalence of coeliac disease in patients with irritable bowel syndrome plus fibromyalgia in comparison with those with isolated irritable bowel syndrome: a case-finding study [PDF]

, 2013
INTRODUCTION: Irritable bowel syndrome (IBS) and fibromyalgia syndrome (FMS) are two common central sensitization disorders frequently associated in the same patient, and some of these patients with IBS plus FMS (IBS/FMS) could actually be undiagnosed of
Blanco, Ignacio, Bobes, Julio, Rodrigo Sáez, Luis Ricardo, Serres, Frederick J. de   +3 more
core   +2 more sources