Results 81 to 90 of about 4,667 (242)

Ursodeoxycholic acid for treatment of cholestasis in patients with hepatic amyloidosis [PDF]

, 2009
Background. Amyloidosis represents a group of different diseases characterized by extracellular accumulation of pathologic fibrillar proteins in various tissues and organs.
Akoglu Bora, Faust Dominik, Milović Vladan, Ristić Gordana   +3 more
core   +1 more source

Anti‐Ro52/TRIM21 autoantibodies predict Sjögren's syndrome in patients with primary biliary cholangitis

Hepatology Research, Volume 55, Issue 8, Page 1128-1138, August 2025.
Abstract Background and aims Sjögren's syndrome is a common comorbidity in patients with primary biliary cholangitis (PBC). Anti‐Ro52 autoantibodies against the protein TRIM21 are often seen in Sjögren's syndrome. TRIM21 consists of four domains (PRY/SPRY, Coiled‐Coil, B‐box, and RING domain), each with a specific function.
Marie Louise Næstholt Dahl, Trine‐Line Korsholm, Jakob Hauge Mikkelsen, Malene Hvid, Ayad Babaee, Matias Hauge Böttcher, Jesper Bach Hansen, Peter Holland‐Fischer, Christian Brix Folsted Andersen, Henning Grønbæk, Bent Deleuran   +10 more
wiley   +1 more source

Drug-induced hepatitis superimposed on the presence of anti-SLA antibody: a case report

Journal of Medical Case Reports, 2008
Introduction Autoimmune hepatitis is a necroinflammatory disorder of unknown etiology characterized by the presence of circulating antibodies, hypergammaglobulinemia, and response to immunosuppression.
Etxagibel Aitziber, Julià M Rosa, Brotons Alvaro, Company M Margarita, Dolz Carlos   +4 more
doaj   +1 more source

Liver Involvement in Celiac Disease and Immune‐Mediated Diseases of the Small Bowel

Liver International, Volume 45, Issue 8, August 2025.
ABSTRACT Disorders of the hepatobiliary system are commonly associated with gastrointestinal (GI) diseases. The GI and hepatobiliary systems interact through the portal vein system and enterohepatic circulation, creating a gut–liver axis that allows for a complex multidirectional interplay between immune, hormonal, dietary and environmental luminal ...
Nicoletta Nandi, Elena F. Verdu, Detlef Schuppan, Andres Jose Gomez‐Aldana, Maria Ines Pinto‐Sanchez, Francesco Simone Conforti, Marco Maggioni, Flavio Caprioli, Luca Elli   +8 more
wiley   +1 more source

Concomitant Case of Primary Biliary Cirrhosis and Autoimmune Hemolityc Anemia Responding to Corticosteroid and Ursodeoxycholic Acid in Young Woman

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2016
Primary biliary cirrhosis (PBC) is an autoimmune liver disease of unknown etiology and is characterized by chronic progressive cholestasis with destruction of the small intrahepatic bile ducts and associated most commonly with antimitochondrial ...
Susanto H Kusuma, Fardah Akil, Amelia Rifai, Rini R Bachtiar, Numan AS Daud, AM Luthfi Parewangi   +5 more
doaj  

Validation of PBC‐10 in Japanese patients with primary biliary cholangitis

Hepatology Research, Volume 55, Issue 7, Page 986-993, July 2025.
This study validates the Japanese version of the PBC‐10, a short‐form health‐related quality of life (HRQOL) assessment tool for patients with primary biliary cholangitis (PBC). The findings confirm its reliability and strong correlation with the PBC‐40, supporting its use for rapid clinical screening of HRQOL impairments in Japanese patients. Abstract
Akihito Takeuchi, Masanori Abe, Sachiko Furukawa, Tadashi Namisaki, Atsushi Takahashi, Kazumichi Abe, Kentaro Kikuchi, Ryo Miura, Naoko Tachizawa, Yoshinari Asaoka, Akinobu Takaki, Yoshiyuki Ueno, Akira Honda, Shuji Terai, Atsumasa Komori, Hiromasa Ohira, Hitoshi Yoshiji, Atsuko Yonezawa, Atsushi Tanaka   +18 more
wiley   +1 more source

Muscle Vasculitis: A Novel Delineation of Distinct Subsets of Disease

ACR Open Rheumatology, Volume 7, Issue 6, June 2025.
Objective The objective of this study was to assess the clinical and histopathologic features of muscle vasculitis. Methods The electronic database of SA Pathology, wherein all muscle biopsy samples in South Australia are assessed, was searched (2000–2023), identifying cases of vasculitis.
Thomas Khoo, Sarah Saxon, Barbara Koszyca, Bernice Gutschmidt, Vidya Limaye   +4 more
wiley   +1 more source

Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis

Journal of Immunology Research, 2017
Formerly termed primary biliary cirrhosis, primary biliary cholangitis (PBC) is a chronic and progressive cholestatic liver disease characterized by the presence of antimitochondrial antibodies.
Satoru Joshita, Takeji Umemura, Eiji Tanaka, Masao Ota   +3 more
doaj   +1 more source

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]

, 1988
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A, Coppel, R, Gershwin, M, Leung, P, Van De Water, Judith   +4 more
core  

Humoral autoimmune response heterogeneity in the spectrum of primary biliary cirrhosis [PDF]

, 2012
To compare autoantibody features in patients with primary biliary cirrhosis (PBC) and individuals presenting antimitochondria antibodies (AMAs) but no clinical or biochemical evidence of disease.A total of 212 AMA-positive serum samples were classified ...
Abrantes-Lemos, Clarice Pires, Andrade, Luiz Eduardo Coelho, Cancado, Eduardo Luiz Rachid, Dellavance, Alessandra, Harriz, Michelle, Marvulle, Valdecir   +5 more
core   +1 more source