In Vitro Susceptibility of Field Isolates of Leishmania donovani to Miltefosine and Amphotericin B: Correlation with Sodium Antimony Gluconate Susceptibility and Implications for Treatment in Areas of Endemicity [PDF]
Antimicrobial Agents and Chemotherapy, 2009 ABSTRACT Indian Leishmania donovani isolates ( n = 19) from regional zones representing various levels of antimony resistance displayed significantly ( P < 0.01) correlated results with respect to in vitro susceptibility to the antileishmanial drugs sodium
Dhiraj, Kumar +3 more
semanticscholar +4 more sources
Journal of Medicine, 1970 A total of fifty consecutive cases of Kala-azar admitted in the medicine units of Rajshahi Medical College Hospital during the period from February 2006 to October 2006 were included in this study. The number of the patients clearly indicates that the burden of Kala-azar in this region is significant and expanding.
Quazi Tarikul Islam +5 more
semanticscholar +4 more sources
Sodium Antimony Gluconate leads to a predominant protective response during Visceral Leishmaniasis on triggering CD2 epitope [PDF]
International Journal of Infectious Diseases, 2018 S. Sinha, S. Sundaram
semanticscholar +3 more sources
Comparison of generic and proprietary sodium stibogluconate for the treatment of visceral leishmaniasis in Kenya [PDF]
Bulletin of the World Health Organization, 2001 OBJECTIVE: To compare the use of generic and proprietary sodium stibogluconate for the treatment of visceral leishmaniasis (kala-azar). METHODS: A total of 102 patients with confirmed kala-azar were treated in a mission hospital in West Pokot region ...
Moore Elinore +6 more
doaj +2 more sources
Post-kala-azar dermal leishmaniasis (PKDL) drug efficacy study landscape: A systematic scoping review of clinical trials and observational studies to assess the feasibility of establishing an individual participant-level data (IPD) platform. [PDF]
PLoS Negl Trop DisBackground: Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis which can occur after successful treatment of visceral leishmaniasis (VL) and is a public health problem in VL endemic areas.
Singh-Phulgenda S +16 more
europepmc +3 more sources
The Indian journal of medical research, 2007 Sodium antimony gluconate (SAG) and miltefosine used in the treatment of kala-azar are known to cause several side effects but severe thrombocytopenia has not been reported. Four cases of severe thrombocytopenia, two caused by SAG and two by miltefosine were promptly detected and treated by immediate withdrawal of the offending drugs, platelet and ...
C P, Thakur +4 more
openaire +2 more sources
The Indian journal of medical research, 2008 Present treatment strategies for kala-azar (visceral leishmaniasis, VL) include use of first line drug sodium antimony gluconate (SAG) to all patients but a large number of patients do not get relief with this drug. If a patient does not respond to a full course of SAG, a second or third line drug is given.
C P, Thakur +3 more
openaire +2 more sources
Leishmaniasis with secondary hemophagocytic syndrome: a case report [PDF]
Zhenduanxue lilun yu shijian, 2022 Leishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors.
XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
doaj +1 more source
Indian journal of dermatology, venereology and leprology, 2007 Drugs used in PKDL include parenteral sodium antimony gluconate (SAG), amphotericin-B, pentamidine, and ketoconazole (KTZ). SAG is the most effective one. Given alone, SAG has to be given for a long duration, leading to poor patient compliance and treatment failure.
S. K. Rathi +3 more
openaire +2 more sources