Mild-Temperature Catalyzed Hydrosilylation for Simplified Carbohydrate Functionalization of Porous Silicon Nanoparticles. [PDF]
ChemistryA one‐pot hydrosilylation strategy is developed for the functionalization of porous silicon nanoparticles (PSiNPs) with allyl‐tetra‐O‐acetyl‐β‐D‐glucopyranoside (ATAG), using mild temperatures and ethylaluminium dichloride solution (EtAlCl2) as a catalyst. This efficient method reduces reaction times for passivating and bioengineering PSiNPs, enhancing
Nolli MG +9 more
europepmc +2 more sources
Observations on the treatment of 25 cases of kala-azar with stibatin (sodium antimony gluconate).
The Indian medical gazette, 2010 R. K. S. Choudhuri
openalex +3 more sources
Genetic markers for SSG-resistance in Leishmania donovani and SSG-treatment failure of visceral leishmaniasis patients in the Indian subcontinent [PDF]
, 2012 The current standard to assess pentavalent antimonial (SSG) susceptibility of Leishmania is a laborious in vitro assay of which the result has little clinical value because SSG-resistant parasites are also found in SSG-cured patients.
Decuypere, Saskia +2 more
core +1 more source
Pricing of drugs and donations: options for sustainable equity pricing. [PDF]
, 2001 Effective medicines exist to treat or alleviate many diseases which predominate in the developing world and cause high mortality and morbidity rates. Price should not be an obstacle preventing access to these medicines.
Ford, N, Herranz, E, Pérez-Casas, C
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Efficacy of Thermotherapy to Treat Cutaneous Leishmaniasis Caused by Leishmania tropica in Kabul, Afghanistan: A Randomized, Controlled Trial [PDF]
, 2005 BACKGROUND: Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful ...
Aram H +23 more
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PLoS Neglected Tropical Diseases, 2013 BackgroundSodium antimony gluconate (SAG) unresponsiveness of Leishmania donovani (Ld) had effectively compromised the chemotherapeutic potential of SAG.
Sanchita Das +8 more
doaj +1 more source
In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]
, 2014 Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
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Snapshot Profiling of the Antileishmanial Potency of Lead Compounds and Drug Candidates against Intracellular Leishmania donovani Amastigotes, with a Focus on Human-Derived Host Cells [PDF]
, 2017 This study characterised in vitro potencies of anti-leishmanial agents against intracellular Leishmania donovani amastigotes in primary human macrophages, obtained with or without CD14-positive monocyte enrichment, phorbol 12-myristate 13-acetate (PMA ...
Alvar +31 more
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Structures, targets and recent approaches in anti-leishmanial drug discovery and development. [PDF]
, 2011 Recent years have seen a significant improvement in available treatment options for leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the treatment of visceral leishmaniasis (VL) in India since 2002.
Seifert, Karin
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Electrocardiogram changes due to sodium stibogluconate treatment of kala-azar [PDF]
, 2023 Background: Kala-azar [visceral leishmaniasis (VL)] is caused by the protozoon Leishmania donovani complex. Without adequate treatment, most patients with clinical VL die due to secondary infections.
Ali, M. Liaquat +3 more
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