Results 51 to 60 of about 6,709 (216)

Hematological profile among cutaneous leishmaniasis patients before and after treatment with sodium stibogluconate in Diyala, Iraq

Journal of Infection in Developing Countries
Introduction: Cutaneous leishmaniasis (CL) is a common protozoan disease in Iraq characterized by localized ulcers, primarily on exposed skin. This study aimed to investigate the hematological parameters of infected patients using a complete blood count
Ghuffran Muhammed Hassan, Hayder Z Ali, Watheq Muhammed Hussein   +2 more
doaj   +1 more source

Leukemic Cells Hijack Stromal Bioelectricity to Reprogram the Bone Marrow Niche via CaV1.2‐Dependent Mechanisms

Advanced Science, Volume 12, Issue 39, October 20, 2025.
Leukemic blasts induce membrane depolarization in mesenchymal stromal cells (MSCs), contributing to a dysfunctional niche that favors leukemia progression. Here, it is demonstrated that restoring the expression of CaV1.2 calcium channel in AML‐MSCs repolarizes their membrane potential, reprogramming them toward a healthy phenotype.
Ambra Da Ros, Maddalena Benetton, Giulia Borella, Giorgia Longo, Giulia Borile, Alice Cani, Diego Lopez‐Pigozzi, Mario Bortolozzi, Silvia Bresolin, Claudia Tregnago, Franco Locatelli, Martina Pigazzi   +11 more
wiley   +1 more source

Further characterization of a secreted lipase from the human pathogen Leishmania donovani by determining the effect of various metal ions on its enzymatic activity. [PDF]

, 2014
Leishmania donovani, a protozoan parasite, is the causative agent of the often fatal disease visceral leishmaniasis. The current treatments available are minimal and toxic to the patient.
Hoertz, Lana
core   +1 more source

Guava root exudate‐driven rhizosphere microorganisms changes transmitted to foliar‐feeding insects influence their feeding behaviour

Plant Biotechnology Journal, Volume 23, Issue 7, Page 2963-2977, July 2025.
Summary The growth of different grafted guava was different as affected by grafting on different rootstock varieties, which also influenced the damage degree of Spodoptera litura larvae. The co‐regulation of the pest gut by rhizosphere microorganisms and root exudates may contribute to this differential damage. In this study, the microorganisms of soil,
Peiwen Zhang, Wei Lu, Lei Yue, Zhixiang Zhang, Xuehua Shao   +4 more
wiley   +1 more source

A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis

Advanced Science, Volume 12, Issue 18, May 15, 2025.
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng, Xinyi Jing, Liuqi Shao, Yakun Wang, Congrui Fu, Hongxiao Yu, Xiaoyi Wang, Xue Zhao, Fanrao Kong, Yake Ji, Xiaochen Tian, Wei He, Shangyu Bi, Luo Shi, Hanqiao Wang, Fang Yuan, Sheng Wang   +16 more
wiley   +1 more source

Managing pregnancy with long‐term parenteral nutrition: A case report and review of the literature

Journal of Parenteral and Enteral Nutrition, Volume 49, Issue 4, Page 528-533, May 2025.
Abstract Parenteral nutrition (PN) is essential for patients with chronic intestinal failure but poses significant challenges during pregnancy because of increased nutrition needs and associated risks such as central line–associated bloodstream infections. We report a case of a 29‐year‐old primigravid woman with Crohn's disease who required chronic PN.
Muhammad Shahzil, Ammad Javaid Chaudhary, Abdullah Sohail, Kamran Haq, Muhammad Zarrar Khan, Yakir Muszkat, Syed‐Mohammed Jafri   +6 more
wiley   +1 more source

Which Whitening Mouthwash With Different Ingredients Is More Effective on Color and Bond Strength of Enamel?

Journal of Esthetic and Restorative Dentistry, Volume 37, Issue 4, Page 960-968, April 2025.
ABSTRACT Objective To examine the effects of six whitening mouthwashes on tooth color and immediate bond strength to the enamel. Materials and Methods Human incisors were divided into seven groups (n = 10) according to mouthwashes (R.O.C.S Black Edition White, Splat White Plus, Colgate Plax White Charcoal, Signal White Now, Listerine Advanced White ...
Elif Varli Tekingur, Fatih Bedir, Muhammet Karadas, Rahime Zeynep Erdem   +3 more
wiley   +1 more source

Sodium stibogluconate cardiotoxicity and safety of generics [PDF]

, 2017
Between April 9 and May 5 2000, an outbreak of fatal cardiotoxicity occurred in Nepal amongst visceralleishmaniasis patients treated with a recently introduced batch of generic sodium stibogluconate (SSG) from GL Pharmaceuticals, Calcutta, India.
Boelaert, M., Chappuis, F., Koirala, S., Loutan, L., Rijal, S., Singh, R.   +5 more
core  

Solution Blow Spinning: An Emerging Nanomaterials‐Based Wound‐Care Technology

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 2, February 2025.
ABSTRACT Application of one‐dimensional nanofibers have witnessed exponential growth over the past few decades and are still emerging with their excellent physicochemical and electrical properties. The driving force behind this intriguing transition lies in their unique high surface‐to‐volume ratio, ubiquitous nanodomains, improved tensile strength ...
Md Salauddin Sk, Ruth Mwangomo, Luke Daniel, Jordon Gilmore   +3 more
wiley   +1 more source

Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline [PDF]

, 2017
Sodium stibogluconate (SSG) is the first-line therapy for visceral leishmaniasis (VL) in south-eastern Nepal. Recent studies from the neighbouring state of Bihar, India, have shown a dramatic fall in cure rates with treatment failure occurring in up to ...
Acharya, P., Bovier, P.A., Chappuis, F., Das, M.L., Desjeux, P., Karki, B.M.S., Koirala, S., Loutan, L., Rijal, S., Singh, R.   +9 more
core