Results 61 to 70 of about 6,709 (216)

TFC‐1326 Compound Reduces Clinical Signs of Skin Aging. Evidence From In Vitro Human Adipose and Skin Models and Pilot Clinical Trial

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 2, February 2025.
ABSTRACT Background Anti‐freeze Glycoproteins (AFGPs) were described to preserve biological materials and protect them from different stresses. Aims The effects of a synthetic anti‐freeze glycoprotein‐based compound, TFC‐1326, on human skin quality and its biological actions were studied. Methods The effects of various concentrations of TFC‐1326 on the
Géraldine Deliencourt‐Godefroy   +7 more
wiley   +1 more source

Rock geochemistry induces stress and starvation responses in the bacterial proteome [PDF]

open access: yes, 2016
Interactions between microorganisms and rocks play an important role in Earth system processes. However, little is known about the molecular capabilities microorganisms require to live in rocky environments.
Anderson   +32 more
core   +1 more source

Can we harness immune responses to improve drug treatment in leishmaniasis? [PDF]

open access: yes, 2020
Leishmaniasis is a vector-borne parasitic disease that has been neglected in priority for control and eradication of malaria, tuberculosis and HIV/AIDS.
Aruleba, Raphael Taiwo   +3 more
core   +1 more source

Clinical risk factors for therapeutic failure in kala-azar patients treated with pentavalent antimonials in Nepal [PDF]

open access: yes, 2017
Drug-related factors and parasite resistance have been implicated in the failure of pentavalent antimonials (Sbv) in the Indian subcontinent; however, little information is available on host-related factors. Parasitologically confirmed kala-azar patients,
Bhandari, S.   +8 more
core  

EPO Deficiency Upregulates GADD45b/p38 MAPK Axis, Mediating Schizophrenia‐Related Synaptic and Cognitive Impairments

open access: yesAdvanced Science, Volume 11, Issue 47, December 18, 2024.
A novel etiopathogenic mechanism of SZ‐related cognitive impairments is uncovered, driven by EPO deficiency and the activation of the GADD45b/p38 MAPK axis. The results highlight potential therapeutic strategies for cognitive deficits in SZ. Abstract Schizophrenia (SZ) is a chronic and severe mental illness associated with psychiatric symptoms ...
Cuiping Guo   +8 more
wiley   +1 more source

Antimonial Resistance in Leishmania donovani Is Associated with Increased In Vivo Parasite Burden [PDF]

open access: yes, 2011
Leishmania donovani is an intracellular protozoan parasite that causes visceral leishmaniasis (VL). Antimonials (SSG) have long been the first-line treatment against VL, but have now been replaced by miltefosine (MIL) in the Indian subcontinent due to ...
AK Haldar   +32 more
core   +3 more sources

Biological Properties, Health Benefits and Semisynthetic Derivatives of Edible Astraeus Mushrooms (Diplocystidiaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, Volume 21, Issue 12, December 2024.
Abstract Edible Astraeus mushrooms are known for their nutritional and culinary benefits and potential therapeutic properties. However, more investigation and discussion are still needed to understand their mechanisms of action regarding observed biological activities and thorough chemical analysis of bioactive compounds.
Alison T. Ung, Hui Chen
wiley   +1 more source

American Tegumentary Leishmaniasis: Is Antimonial Treatment Outcome Related to Parasite Drug Susceptibility? [PDF]

open access: yes, 2017
BackgroundAntimonials are the first drug of choice for the treatment of American tegumentary leishmaniasis (ATL); however, their efficacy is not predictable, and this may be linked to parasite drug resistance.
Adui, Vanessa   +11 more
core  

Prevention of complications for hospitalized patients receiving parenteral nutrition: A narrative review

open access: yesNutrition in Clinical Practice, Volume 39, Issue 5, Page 1037-1053, October 2024.
Abstract Hospitalized patients may benefit from parenteral nutrition to address their compromised nutrition status attributed to limited oral/enteral intake and increased nutrient/energy requirement during acute illness. Parenteral nutrition, however, can be associated with many complications that can negatively impact patient outcomes. In this review,
Dina Al‐Zubeidi   +2 more
wiley   +1 more source

Drug Resistance in Visceral Leishmaniasis [PDF]

open access: yes, 2010
Visceral leishmaniasis remains a public health problem worldwide. This illness was included by the World Health Organization in the list of neglected tropical diseases targeted for elimination by 2015.
Maltezou, Helena C.
core   +4 more sources

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