Results 61 to 70 of about 6,678 (215)
Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline [PDF]
, 2017 Sodium stibogluconate (SSG) is the first-line therapy for visceral leishmaniasis (VL) in south-eastern Nepal. Recent studies from the neighbouring state of Bihar, India, have shown a dramatic fall in cure rates with treatment failure occurring in up to ...
Acharya, P. +9 more
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Advanced Science, Volume 11, Issue 47, December 18, 2024.A novel etiopathogenic mechanism of SZ‐related cognitive impairments is uncovered, driven by EPO deficiency and the activation of the GADD45b/p38 MAPK axis. The results highlight potential therapeutic strategies for cognitive deficits in SZ. Abstract Schizophrenia (SZ) is a chronic and severe mental illness associated with psychiatric symptoms ...
Cuiping Guo +8 more
wiley +1 more source
American Tegumentary Leishmaniasis: Is Antimonial Treatment Outcome Related to Parasite Drug Susceptibility? [PDF]
, 2017 BackgroundAntimonials are the first drug of choice for the treatment of American tegumentary leishmaniasis (ATL); however, their efficacy is not predictable, and this may be linked to parasite drug resistance.
Adui, Vanessa +11 more
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Chemistry &Biodiversity, Volume 21, Issue 12, December 2024.Abstract Edible Astraeus mushrooms are known for their nutritional and culinary benefits and potential therapeutic properties. However, more investigation and discussion are still needed to understand their mechanisms of action regarding observed biological activities and thorough chemical analysis of bioactive compounds.
Alison T. Ung, Hui Chen
wiley +1 more source
Drug Resistance in Visceral Leishmaniasis [PDF]
, 2010 Visceral leishmaniasis remains a public health problem worldwide. This illness was included by the World Health Organization in the list of neglected tropical diseases targeted for elimination by 2015.
Maltezou, Helena C.
core +4 more sources
Nutrition in Clinical Practice, Volume 39, Issue 5, Page 1037-1053, October 2024.Abstract Hospitalized patients may benefit from parenteral nutrition to address their compromised nutrition status attributed to limited oral/enteral intake and increased nutrient/energy requirement during acute illness. Parenteral nutrition, however, can be associated with many complications that can negatively impact patient outcomes. In this review,
Dina Al‐Zubeidi +2 more
wiley +1 more source
Clinical risk factors for therapeutic failure in kala-azar patients treated with pentavalent antimonials in Nepal [PDF]
, 2017 Drug-related factors and parasite resistance have been implicated in the failure of pentavalent antimonials (Sbv) in the Indian subcontinent; however, little information is available on host-related factors. Parasitologically confirmed kala-azar patients,
Bhandari, S. +8 more
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Rock geochemistry induces stress and starvation responses in the bacterial proteome [PDF]
, 2016 Interactions between microorganisms and rocks play an important role in Earth system processes. However, little is known about the molecular capabilities microorganisms require to live in rocky environments.
Anderson +32 more
core +1 more source
Advanced Materials, Volume 36, Issue 35, August 28, 2024.Nucleophilic oxidation (NOR) has great potential as an alternative to OER. NOR offers faster kinetics, generates high‐value products, and reduces energy consumption. By coupling NOR with hydrogen evolution reaction, hydrogen production efficiency can be enhanced while yielding valuable by‐products or degrading pollutants.
Peng Wang +11 more
wiley +1 more source
Role of ABC transporter MRPA, γ-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani [PDF]
, 2007 Objectives: The resistance of clinical isolates of Leishmania donovani to sodium antimony gluconate (SAG), the mainstay of treatment in Indian visceral leishmaniasis, has become a critical issue in India.
Chatterjee, Mitali +7 more
core +1 more source