Results 41 to 50 of about 9,159,657 (214)
Evaluation of antimutagenic effect of todralazine in cultured lymphocytes [PDF]
Mutagenesis, 2000 Todralazine, an antihypertensive drug from the hydrazinophthalazine group, significantly decreased the activities of benzo[a]pyrene and mitomycin C in three short-term genotoxicity tests in human lymphocyte cultures. The thioguanine resistance test, the cytokinesis-blocked micronucleus assay and the sister chromatid exchange test were used to ...
K, Gasiorowski, B, Brokos
openaire +2 more sources
Dual Genotoxic and Antigenotoxic Effects of 3‐Benzoylcoumarins in Mammalian Cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Coumarins are phenolic compounds widely recognized for their diverse pharmacological activities and have attracted increasing attention as potential chemopreventive agents. In the present study, four known 3‐benzoylcoumarin derivatives [(1), (2), (3), and (4)] were evaluated for their cytotoxic, mutagenic, and antigenotoxic effects in Chinese ...
Leticia Helena Parreira +7 more
wiley +1 more source
JSFA reports, Volume 5, Issue 3, Page 91-103, March 2025.Abstract Background Fennel (Foeniculum vulgare Mill.) is a widely cultivated vegetable and aromatic‐medicinal plant. In this research, field studies assessed 12 fennel genotypes of diverse origin, comprising 10 Greek accessions and two European commercial varieties, focusing on their morpho‐agronomical traits, phenolic compounds and antioxidant ...
Kalliopi I. Kadoglidou +6 more
wiley +1 more source
The mutagenic and antimutagenic activity of Sutherlandia frutescens extracts and marker compounds
BMC Complementary and Alternative Medicine, 2018 Background Sutherlandia frutescens (L.) R. Br is endemic to Southern Africa where it has been traditionally used for cancer and diabetes. In recent times it has been marketed for its reputed (but not proven) anticancer, antidiabetic and anti-HIV ...
Siyabulela S. B. N. Ntuli +2 more
doaj +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
, 2018 A methanol extract of the dried leaves of Lansium domesticum showed antimutagenic effects against 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) and 2-amino-1-methyl-6-phenylimidazo[4,5-bI]pyridine (PhIP) using the Ames assay.
Stephen Teo (5866058) +7 more
core +1 more source
Antimutagenicity effect of Citrus nobilis
Archives of Advances in Biosciences, 2013 Currently cancer is considered as one of the main factors of mortality globally. Many chemicals in our environment can cause genetic mutations and are potentially responsible for millions of cancer-related deaths. Nowadays the scientists are looking for food materials which can potenthially prevent the cancer occurrence. The purpose of this research is
Entezari, Maliheh, Hosseini, Seyed Javad
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Applied Research, Volume 5, Issue 5, October 2026.Cissus quadrangularis stem peel‐derived bio salt protects SH‐SY5Y neuroblastoma cells against streptozotocin‐induced neurotoxicity by reducing oxidative stress, suppressing apoptosis, and improving cell viability. These findings highlight its potential as a natural neuroprotective agent for neurodegenerative disorders.
Panimalar Thirupathi Brindhavanam +4 more
wiley +1 more source
, 2002 Almost two thirds of the world population consume tea everyday. Tea is processed differently in different parts of the world to give green (20%), black (78%) or oolong tea (2%).
Giri, Ashok K +4 more
core +1 more source
Advances in Pharmacological Sciences, 2019 Introduction. Honey bee venom (HBV) has various biological activities such as the inhibitory effect on several types of cancer. Cisplatin is an old and potent drug to treat most of the cancers.
Faranak Shiassi Arani +3 more
doaj +1 more source