Results 121 to 130 of about 22,037,861 (287)
TOTAL SYNTHESIS OF ANTIMYCIN A3
M, Kinoshita +3 more
openaire +3 more sources
TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga +15 more
wiley +1 more source
The Chemical Studies of Antimycin A. I Separation of Antimycin A
Uzu, Keizō +3 more
openaire +1 more source
Abstract In hypoxic environments, fish attempt to regulate their metabolic rate as oxygen levels in the water decline. Individuals that have low energy requirements for maintenance – standard metabolic rate (SMR) – are expected to have higher hypoxia tolerance, measured as the critical water oxygen saturation threshold (Scrit) below which they cannot ...
Elisa Thoral +11 more
wiley +1 more source
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang +9 more
wiley +1 more source
A Color-Tuning Bioluminescent Sensor (AmyLuc) for Real-Time Monitoring of Intracellular pH Dynamics in Cancer Cells. [PDF]
Bevilaqua VR +6 more
europepmc +1 more source
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai +7 more
wiley +1 more source
β-Lapachone-Induced Oxidative Stress Causes PARP-Dependent NAD<sup>+</sup>-Depletion that Affects the Energy Metabolism of Cultured Primary Rat Astrocytes. [PDF]
Willker JE, Dringen R.
europepmc +1 more source
Abstract Anorexia nervosa (AN) is a psychiatric disorder characterized by prolonged caloric restriction and skeletal muscle atrophy. Mitochondrial health is a key mediator of muscle function, yet the role of mitochondria during AN and following weight regain has not been investigated. The objective of this study was to evaluate mitochondrial capacities
Megan E. Rosa‐Caldwell +12 more
wiley +1 more source

