Results 141 to 150 of about 22,037,861 (287)

Deficiency of microRNA-10a in CD4+ T cells protects against intestinal infection through mitochondrial oxidation-IL-22 pathway. [PDF]

J Immunol
Yang W, Yu T, Yao S, Cong Y.
europepmc   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons. [PDF]

Autophagy Rep
O'Callaghan B, Melandri D, Soltic D, Cosker K, Soutar MPM, Evans JR, Lucas-Clarke H, Robin J, Gandhi S, Birsa N, Arber C, Wray S, Plun-Favreau H.   +12 more
europepmc   +1 more source

APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function

The Journal of Physiology, EarlyView.
Abstract figure legend We examined the interaction effect of ovarian hormones and APOE genotype on cerebrovascular and mitochondrial function. Our data revealed that APOEε3 mice that were ovariectomized exhibited impaired endothelial function and greater oxidative stress and inflammation compared to sham controls.
Mackenzie N. Kehmeier, Alexandra Famiano, Abigail E. Cullen, Thomas Leonhardt, Skylyn J. Ferguson, Madeleine Snyder, Carrie E. McCurdy, Daniel J. Tyrrell, Nabil J. Alkayed, Ashley E. Walker   +9 more
wiley   +1 more source

Ectopic expression of cytosolic DHODH uncouples de novo pyrimidine biosynthesis from mitochondrial electron transport. [PDF]

Nat Metab
Curtabbi A, Jaroszewicz SN, Sanz-Cortés R, Acín-Pérez R, Prymidis D, Cherevatenko M, Martínez-de-Mena R, Esteban-Amo MJ, de la Fuente MA, Frezza C, Enríquez JA.   +10 more
europepmc   +1 more source

Sprint‐interval training with post‐exercise blood flow restriction increases mitochondrial content and respiration

The Journal of Physiology, EarlyView.
Abstract figure legend The mechanisms underpinning improved maximal oxygen uptake following sprint interval training (SIT) with post‐exercise blood flow restriction (BFR), compared to SIT alone, remain unclear. This study examined the effects of 6 week SIT with (BFR; n = 12) or without (CON; n = 8) post‐exercise BFR on V̇O2peak${{\dot{V}}_{{{{\mathrm{O}
Donald L. Peden, Carolin Stangier, Emma A. Mitchell, Stephen J. Bailey, Richard A. Ferguson   +4 more
wiley   +1 more source

Light‐Activated Isolation of High‐Quality Mitochondria for Therapeutic Transplantation

Angewandte Chemie, Volume 138, Issue 28, 6 July 2026.
The Light‐Activated Mitochondrial Isolation (LAMI) platform enables the selective and non‐destructive isolation of high‐purity, metabolically active mitochondria. By integrating modular, ligand‐programmable magnetic probes with photo‐cleavable release, LAMI overcomes long‐standing limitations of conventional isolation methods and provides a robust ...
Hui Liu, Yuxin Jiao, Ting Zhang, Haiwei Wang, Yufei Xue, Jiayu Ding, Yang Ding, Meiling Wang, Weisen Zhang, Hua Bai, Bo Peng, Nicolas H. Voelcker, Lin Li   +12 more
wiley   +2 more sources

STUDIES ON THE BIOSYNTHESIS OF ANTIMYCIN A

The Journal of Antibiotics, 1972
NIVARD NEFT, THOMAS M. FARLEY
openaire   +2 more sources

Progeny effects of rotenone exposure depend on parental toxicity. [PDF]

Toxicol Sci
Bergemann CM, Mello DF, Chitrakar R, Fisher K, Bijwadia SR, Huayta J, Ryde IT, Presman R, Huang Z, Herring AH, Murphy SK, Baugh LR, Meyer JN.   +12 more
europepmc   +1 more source