Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos +4 more
wiley +1 more source
Bridging nanomechanics and bioenergetics of single mitochondria by atomic force microscopy. [PDF]
Zorikova EO +5 more
europepmc +1 more source
Utilization by yeast of D-lactate and L-lactate as sources of energy in the presence of antimycin A.
P. Pajot, M. Claisse
semanticscholar +1 more source
Identification of drug repurposing candidates for the treatment of polycystic kidney disease
Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer +9 more
wiley +1 more source
Extracellular flux analyses indicate low ATP yield and require refinement for accurate determination of maximal oxygen consumption rate. [PDF]
Ransy C +9 more
europepmc +1 more source
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon +27 more
wiley +1 more source
Cyclic electron flow around photosystem I provides energy production and photoprotection in C4 plants. [PDF]
Nakamura A +5 more
europepmc +1 more source
Influence of antimycin a and uncouplers on anaerobic photosynthesis in isolated chloroplasts.
R. Slovacek, Geoffrey Hind
semanticscholar +1 more source
Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He +6 more
wiley +1 more source
Energy substrate preference and metabolic flexibility in quiescent and oxytocin-stimulated human myometrial cells. [PDF]
Prifti KK +6 more
europepmc +1 more source

