Results 171 to 180 of about 22,037,861 (287)

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta-Cell Function. [PDF]

FASEB J
Lloyd M, Vedovato N, Mullan SJ, Elphick A, Dumenil AJ, Rufer C, Title AC, Yesildag B, Haythorne E, Ashcroft FM.   +9 more
europepmc   +1 more source

Biallelic Loss‐Of‐Function Variant in ATP5ME Is Associated With Severe and Early Onset Oxidative Phosphorylation Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT ATP synthase (complex V) catalyzes ATP synthesis and is composed of the F1 catalytic sector and the F0 proton‐conducting sector. The e subunit of the F0 sector, encoded by ATP5ME, is essential for complex V dimerization and cristae organization; however, genetic variants in ATP5ME have not yet been implicated in human disease. We ascertained a
Pranavi Hegde, Aakanksha Anand, Rita Rani, Namanpreet Kaur, Ami Shah, Shilpa Kulkarni, Janani Supraja Mallavaram, Raghavender Medishetti, Amoolya Kandettu, Huzail Shaikh, Shahyan Siddiqui, Purvi Majethia, Vivekananda Bhat, Periyasamy Radhakrishnan, Aarti Sevilimedu, Sanjiban Chakrabarty, Anju Shukla   +16 more
wiley   +1 more source

INHIBITION OF AN ELECTRON TRANSPORT COMPONENT BY ANTIMYCIN A

Journal of Biological Chemistry, 1952
V R, POTTER, A E, REIF
openaire   +2 more sources

Mitochondrial respiration in human peripheral blood mononuclear cells: methodology and influence of permeabilization and storage. [PDF]

Front Mol Biosci
Sekine S, Chamkha I, Elmér E, Åsander Frostner E, Westerlund E, Liu T, Ehinger J, Sjövall F, Uchino H, Elmér E.   +9 more
europepmc   +1 more source

Induction of the AOX1D isoform of alternative oxidase in A. thaliana T-DNA insertion lines lacking isoform AOX1A is insufficient to optimize photosynthesis when treated with antimycin A.

Molecular Plant, 2009
Inga Strodtkötter, K. Padmasree, Challabathula Dinakar, Birgit Speth, P. Niazi, J. Wojtera, I. Voss, P. Do, A. Nunes‐Nesi, A. Fernie, Vera Linke, A. S. Raghavendra, R. Scheibe   +12 more
semanticscholar   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

p53-mediated regulation of electron transport chain and nucleotide synthesis during Newcastle disease virus infection. [PDF]

J Virol
Zhao C, Tang N, Wang J, Qu Y, Tan L, Song C, Qiu X, Liao Y, Luo T, Ding C, Sun Y.   +10 more
europepmc   +1 more source

Protocol for Seahorse 3D Mito Stress assay in patient-derived atypical teratoid rhabdoid tumor CHLA-05-ATRT single neurospheres. [PDF]

STAR Protoc
Tocci S, Tsai JW.
europepmc   +1 more source

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

Aging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang, Suyeon Choi, Soo‐Jin Kim, Sooyun Kim, Dong Hyun Jo, Tae Geol Lee, Kyu‐Sang Park, Jeong Hun Kim   +7 more
wiley   +1 more source

UBE4B Mediates Mitophagy via NIPSNAP1 Ubiquitination and NDP52 Recruitment. [PDF]

Int J Mol Sci
Jin B, Qu J, Xu K, Zhang Y, Xu P, Wang X, Zhao B, Jiao X.   +7 more
europepmc   +1 more source