Results 11 to 20 of about 84,503 (119)
Medicina, 2021 Background and Objectives: Ovarian surgical ablation (OSA) in estrogen receptor-positive (ER+) breast cancer is usually performed to halt ovarian function in premenopausal patients.
Joana Correia Oliveira +3 more
doaj +1 more source
Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1 [PDF]
Journal of Biological Chemistry, 2003 The purine anti-metabolite 6-mercaptopurine is one of the most widely used drugs for the treatment of acute childhood leukemia and chronic myelocytic leukemia. Developed in the 1950s, the drug is also being used as a treatment for inflammatory diseases such as Crohn's disease. The antiproliferative mechanism of action of this drug and other purine anti-
Peter, Ordentlich +3 more
openaire +2 more sources
The seventieth anniversary of the hormonal treatment of prostatic carcinoma [PDF]
Archive of Oncology, 2011 Hormonal treatment of prostatic carcinoma was initiated in the first half of twentieth century. Theoretical basis of hormonal treatment was established with the work of Charles Brenton Huggins published in 1941.
Milovanović Lela
doaj +1 more source
Primary endocrine therapy of locally advanced breast cancer patients [PDF]
Archive of Oncology, 2003 Primary endocrine therapy has been traditionally reserved for elderly and unfit locally advanced breast cancer patients (LABC patients). In this group, the primary endocrine therapy could not be adequately compared to primary chemotherapy.
Nešković-Konstantinović Zora B.
doaj +1 more source
Treatment of metastatic breast cancer with anastrozole in patients previously treated with aminoglutethimide - case report [PDF]
Archive of Oncology, 2003 Anastrozole represents new, strong and selective nonsteroid aromatase inhibitor. The purpose of this report was to show the effect of anastrozole in two patients with breast cancer who were previously treated with aminoglutethimide. A female patient aged
Boškov Nedeljka
doaj +1 more source
Acta Médica Portuguesa, 2023 Introduction: Genomic assays are useful tools for tailoring adjuvant treatment in early breast cancer. We aimed to analyse the role of an institutional protocol of a genomic assay for chemotherapy de-escalation.
Diogo Martins-Branco +6 more
doaj +1 more source
EO771, the first luminal B mammary cancer cell line from C57BL/6 mice
Cancer Cell International, 2020 Background Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatment and to understand the prognosis
Augustin Le Naour +11 more
doaj +1 more source
Antiestrogen therapy in recurrent ovarian cancer resulting in 28 months of stable disease: A case report and review of the literature [PDF]
Archive of Oncology, 2010 Hormonal therapy for adjuvant treatment of ovarian cancer may provide a low toxicity option in some patients with refractory disease. A 53 year-old patient with stage IIIC papillary serous ovarian cancer previously treated with multiple chemotherapy ...
Carter Jori +4 more
doaj +1 more source
Sexual quality of life in hormonotherapy for breast cancer patients
Brazilian Journal of Oncology, 2022 Objectives: To evaluate how hormonal therapy can impact breast cancer patients sexual quality of life and compare two widely used therapeutic agents: anastrozole and tamoxifen. Studies so far have evaluated the side effects of such therapy on
Pedro Paulo Perroni da Silva +7 more
doaj +1 more source
The effect of systemic and topical ophthalmic medications on choroidal thickness: A review
British Journal of Clinical Pharmacology, 2022 The choroid plays an important role in various ocular pathologies and retinal blood supply. There is a knowledge gap on how the choroid is affected by systemic and topical medications.
Shanna C. Yeung +4 more
semanticscholar +1 more source