Psoriatic arthritis patients have increased morbidity already at the time of diagnosis: a case-control study. [PDF]
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HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
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Post-Marketing Requirements for Anticancer Drugs Approved in Japan, 2001-2024: A Cross-Sectional Analysis. [PDF]
Tsuno A, Kitagaki H, Maeda H.
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Impact of Reporter Type on Signal Detection of Cancer Therapy-Induced Alopecia: A Hypothesis-Generating Study Using the FDA Adverse Event Reporting System. [PDF]
Yajima A, Uesawa Y.
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Shared decision-making in prostate cancer treatment: selecting an androgen deprivation therapy option. [PDF]
Collins SP, Maculaitis MC, Chakoian M.
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Chlorogenic Acid Attenuates Busulfan-Induced Azoospermia in Rats: Antioxidant-Mediated Restoration of Spermatogenesis and Steroidogenesis - A Stereological and Molecular Analysis. [PDF]
Koohpeyma F, Karimi S.
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Pharmaceutical Utilization Review: A Five-Year Time Trend Analysis of the Pharmaceutical Market in Iran. [PDF]
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Abstract A multidrug-resistant variant of the human breast cancer cell line MCF-7 exhibits multiple biochemical changes including reduced estrogen receptor and increased EGF receptor levels, overexpression of the putative drug efflux pump and cross-resistance to carcinogens, estrogens and antiestrogens .
K H Cowan, Kenneth H Cowan
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Ketoconazole has been recently used in the primary treatment of patients with metastatic cancer of the prostate and is identified as a potent inhibitor of cytochrome P450-dependent adrenal and testicular androgen production. The drug has also shown activity in patients failing conventional hormonal manipulation. We subsequently showed that ketoconazole
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