Results 211 to 220 of about 1,663,582 (244)

Potential Involvement of Redox and Inflammatory Signalling in the Antihyperglycemic and Antioxidant Effects of Harmaline in Male Mice With Type 2 Diabetes

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia   +5 more
wiley   +1 more source

Pharmaceutical Utilization Review: A Five-Year Time Trend Analysis of the Pharmaceutical Market in Iran. [PDF]

open access: yesIran J Pharm Res
Nemati M   +6 more
europepmc   +1 more source

A pleiotropic response associated with resistance of breast cancer cells to antineoplastic drugs and hormonal agents

Trends in Pharmacological Sciences, 1988
Abstract A multidrug-resistant variant of the human breast cancer cell line MCF-7 exhibits multiple biochemical changes including reduced estrogen receptor and increased EGF receptor levels, overexpression of the putative drug efflux pump and cross-resistance to carcinogens, estrogens and antiestrogens .
K H Cowan, Kenneth H Cowan
exaly   +3 more sources

Synergistic effect of ketoconazole and antineoplastic agents on hormone-independent prostatic cancer cells.

Clinical and investigative medicine. Medecine clinique et experimentale, 1990
Ketoconazole has been recently used in the primary treatment of patients with metastatic cancer of the prostate and is identified as a potent inhibitor of cytochrome P450-dependent adrenal and testicular androgen production. The drug has also shown activity in patients failing conventional hormonal manipulation. We subsequently showed that ketoconazole
T, Eichenberger   +3 more
openaire   +1 more source

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