Formamidines with antinociceptive and antiinflammatory activities.
Pursuing our investigations on 7-amino-2,3-polymethyleneindole derivatives, a set of 7-(dimethylaminomethylene)-amino-2,3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic and antiinflammatory activities.
R. CERRI +6 more
openaire +3 more sources
Involvement of μ-opioid receptor on the antinociception induced by supraspinal administration of Tyr-D-Pro-Trp-Gly-NH_2 [PDF]
We have previously reported that Tyr-D-Pro-Trp-Gly-NH_2 (D-Pro^2-Tyr-W-MIF-1) given spinally produces clearly a dose-dependent attenuation of the antinociception induced by Tyr-W-MIF-1 without affecting endomorphins- and[D-Ala^2, NMePhe^4, Gly(ol)^5 ...
サクラダ, シノブ +11 more
core
EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2-Mediated µ-Opioid Receptor Internalization. [PDF]
Peng B +7 more
europepmc +1 more source
Opioid Peptide Hybrids as Multifunctional Analgesic Ligands: Emphasis on Intracellular Signaling. [PDF]
Cecherz I +5 more
europepmc +1 more source
Pekka Talke,1 Isabel Talke2 1Department of Anesthesia and Perioperative Medicine, University of California San Francisco, San Francisco, CA, USA; 2California Polytechnic State University, San Luis Obispo, CA, USACorrespondence: Pekka Talke, Email talkep ...
Talke P, Talke I
doaj
Impact of Δ<sup>9</sup>-tetrahydrocannabinol and oxycodone coadministration on measures of antinociception, dependence, circadian activity, and reward in mice. [PDF]
Slivicki RA +7 more
europepmc +1 more source
Acute Submaximal Running Potentiates the Straub Tail Response to Meperidine in a Dose- and Sex-Dependent Manner in Mice. [PDF]
Nery T +4 more
europepmc +1 more source
Mu opioid receptors gate the locus coeruleus pain generator. [PDF]
Kuo CC +10 more
europepmc +1 more source
Systemic injections of alpha-1 adrenergic agonists produce antinociception in the formalin test
The role of alpha 1 receptors in antinociception was investigated in the formalin test, a well established test of tonic pain. The effect of systemic injections of selective alpha 1-adrenergic agonists (phenylephrine and methoxamine), a mixed alpha ...
core +1 more source
Cannabinoid efficacy for pain: dose, chronicity and route. [PDF]
Ellioff KJ +4 more
europepmc +1 more source

