Results 81 to 90 of about 14,174 (200)

Chronic psychostimulant exposure to adult, but not periadolescent rats reduces subsequent morphine antinociception

, 2012
Preweanling methylphenidate (MPH) exposure produces a long lasting enhanced sensitivity to opioids. Two important questions are whether this enhancement is specific to the age of psychostimulant exposure and the type of psychostimulant.
Cyr, Michelle C, Ingram, Susan L, Aicher, Sue A, Morgan, Michael M   +3 more
core   +1 more source

Anti-nociceptive effects of low dose ketamine in mice may be mediated by the serotonergic systems

Psychiatry and Clinical Psychopharmacology, 2019
OBJECTIVE: In pain management, alternative medications are necessary due to the development of tolerance to traditional opioid analgesics. Literature data suggest that N-methyl-D-aspartate (NMDA) receptor antagonizing drugs can induce antinociception ...
Meral Erdinc, Emre Uyar, Ilker Kelle, Hasan Akkoc   +3 more
doaj   +1 more source

Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats

, 2018
This article contains supportive data related to a research article entitled “Age-dependent antinociception and behavioral inhibition by morphine” (Paul et al., 2018) [1].
Alok Kumar Paul, Nuri Gueven, Nikolas Dietis   +2 more
core   +2 more sources

Efeitos antinociceptivos e sedativos da buprenorfina, da acepromazina ou da associação buprenorfina e acepromazina em gatos Antinociceptive and sedative effects of buprenorphine, acepromazine, or combination of both, in conscious cats

Ciência Rural, 2010
O efeito antinociceptivo da buprenorfina tem sido relatado em cães e gatos. No presente estudo, avaliou-se o limiar nociceptivo mecânico em felinos tratados com buprenorfina, acepromazina ou ambas associadas e foram comparados os efeitos antinociceptivos
Luciana Alvarez Santana, Stelio Pacca Loureiro Luna, Paulo Vinicius Mortensen Steagall, Tatiana Henriques Ferreira, Polly Taylor, Mike Dixon   +5 more
doaj  

An Opioidergic Cortical Antinociception Triggering Site in the Agranular Insular Cortex of the Rat that Contributes to Morphine Antinociception

, 1996
We report an anatomically defined opioid-responsive site in the rostral agranular insular cortex (RAIC) of the rat and characterize the antinociception produced by morphine acting within this region.
L. Jasmin, Jinwen Tang, Adam R. Burkey, Julia J. Wenniger, Earl Carstens   +4 more
core   +1 more source

INFLUENCE OF GLYCINE ON MORPHINE-INDUCED ANTINOCICEPTION IN MICE

, 1990
The effects of glycine on morphine-induced antinociception were investigated in mice, using a cutaneous thermal test (hot-plate), a visceral chemical test (acetylcholine writhing test), and a locomotor activity test.
CIMA L, GIUSTI, PIETRO, ZAMPIRON S, CARRARA, MARIA, CAPOLONGO, FRANCESCA   +4 more
core   +1 more source

Relative contribution of the dorsal raphe nucleus and ventrolateral periaqueductal gray to morphine antinociception and tolerance in the rat

, 2016
The dorsal raphe nucleus (DRN) is embedded in the ventral part of the caudal periaqueductal gray (PAG). Electrical or chemical activation of neurons throughout this region produces antinociception. The objective of this manuscript is to determine whether
Campion, Kyle N, Saville, Kimber A, Morgan, Michael M   +2 more
core   +1 more source

Antinociceptive and antitumor activity of novel synthetic mononuclear Ruthenium (II) compounds

Journal of Research in Medical Sciences, 2013
Background: From the thousands of years, metal compounds have been used in medicine for treatment of various diseases including various types of cancers.
A Shyam Sunder, Satyavati Dhulipala, Sreekanth Thota, Rajeshwar Yerra, Jan Balzarini, Erik De Clercq   +5 more
doaj  

THE OMEGA CONOPEPTIDE TOXIN, LECONOTIDE, GIVEN INTRAVENOUSLY INCREASES MORPHINE ANTINOCICEPTION IN RAT PROSTATE BONE CANCER PAIN

, 2009
THE OMEGA CONOPEPTIDE TOXIN, LECONOTIDE, GIVEN INTRAVENOUSLY INCREASES MORPHINE ANTINOCICEPTION IN RAT PROSTATE BONE CANCER ...
L Aurini (21794609), A Kolosov (21794489), C Goodchild (17754279), E Williams (11760059), I Cooke (9618767)   +4 more
core  

Opioid-monoamine interactions in spinal antinociception: evidence for serotonin but not norepinephrine reciprocity

, 1988
Anatomical and electrophysiological studies have demonstrated that enkephalinergic, noradrenergic, and serotonergic pathways projecting from the brain-stem to the dorsal horn inhibit nociceptive transmission at the spinal level.
Goldstein, Frederick J., Kellstein, D. E., Malseed, R. T.   +2 more
core