Results 71 to 80 of about 6,574,899 (309)

Phenylselanyl Group Incorporation for “Glutathione Peroxidase-Like” Activity Modulation

Molecules, 2020
The ability of organoselenium molecules to mimic the activity of the antioxidant selenoenzyme glutathione peroxidase (GPx) allows for their use as antioxidant or prooxidant modulators in several diseases associated with the disruption of the cell redox ...
Magdalena Obieziurska-Fabisiak, Agata J. Pacuła, Lucia Capoccia, Joanna Drogosz-Stachowicz, Anna Janecka, Claudio Santi, Jacek Ścianowski   +6 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Antioxidant Activity of Endophytic Fungi Isolated from Green and Brown Algae

Journal of Pure and Applied Microbiology
Endophytic fungi have attracted considerable attention because of their diverse bioactive compounds and potential pharmaceutical applications. In this study, we investigated the antioxidant activity of endophytic fungi isolated from green and brown algae.
A.K. Ramya, K. Sethumadhavan, R. Devika
doaj   +1 more source

Antioxidant Activity of Ethanol Extract of Polygonum pulchrum Blume

Pharmacology and Clinical Pharmacy Research, 2016
The use of antioxidants from natural resources has attracted increasing interest. One of the plant that was empirically used as an antioxidant dietary supplement was Polygonum pulchrum Blume (P. pulchrum Blume).
Asman Sadino, Idin Sahidin, Wahyuni Wahyuni   +2 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Nutraceutical antioxidant potential and polyphenolic profiles of the Zambian market classes of bambara groundnuts (Vigna subterranea L. Verdc) and common beans (Phaseolus vulgaris L.) [PDF]

, 2013
Includes abstract.Includes bibliographical references.There is a growing interest in legumes and legume based foods because of the health claims associated with their consumption. The aim of the current study was to explore the nutraceutical potential of
Nyau, Vincent
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Comparative analysis of secondary metabolites contents in[i] Fragaria vesca[/i] L. fruits

Annals of Agricultural and Environmental Medicine, 2014
[i]Fragaria vesca[/i] (wild strawberry) belongs to the Rosaceae family. Besides the leaves ([i]Fragariae folium[/i]) and roots ([i]Fragariae radix[/i]), the aromatic fruits ([i]Fragariae fructus[/i]) of wild strawberry are also herbal materials used in ...
Agnieszka Najda, Jan Dyduch, Magdalena Dyduch-Siemińska, Magdalena Gantner   +3 more
doaj  

Comparison of cytotoxicity, antioxidation and hypoglycemic activity of three stilbene compounds

Shipin yu jixie
ObjectiveTo explore the differences in cytotoxicity, antioxidant, and hypoglycemic activities of resveratrol, oxy-resveratrol, and piceatannol, three stilbene compounds with similar structures.MethodsThe cytotoxicity, extracellular/intracellular ...
CHEN Ying, ZHANG Chaobing, CHEN Shaoqiang, YAN Rian, CHEN Yongsheng   +4 more
doaj   +1 more source

Effects of Organic Acids, Amino Acids and Phenolic Compounds on Antioxidant Characteristic of Zhenjiang Aromatic Vinegar

Molecules, 2019
Zhenjiang aromatic vinegar (ZAV) is one of the famous Chinese vinegars, which contains various physicochemical and bioactive compositions. In the present study, physicochemical properties and total antioxidant activity were detected in ZAV samples.
Bo Zhang, Ting Xia, Wenhui Duan, Zhujun Zhang, Yu Li, Bin Fang, Menglei Xia, Min Wang   +7 more
doaj   +1 more source