Results 61 to 70 of about 717,691 (315)

Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells [PDF]

open access: yes, 2012
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key transcription factor regulating a plethora of detoxifying enzymes and antioxidant genes involved in drug metabolism and defence against oxidative stress.
Denise V. Kratschmar (165140)   +35 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

The Antioxidant Activity of Maltese Honey [PDF]

open access: yesJournal of Apicultural Science, 2014
Abstract Maltese honey has been valued for its medicinal properties since ancient times, so much so that the word Malta is derived from the ancient Greek word, Melite, which means honey. In this study, Maltese honey samples (n = 30) from three harvest seasons and different floral sources were analysed to determine
Meinen, Natacha   +2 more
openaire   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Preparation of antioxidant peptides from Moringa oleifera leaves and their protection against oxidative damage in HepG2 cells

open access: yesFrontiers in Nutrition, 2022
Moringa oleifera leaves are a kind of new food raw materials, rich in functional factors, M. oleifera leaves aqueous extract have antioxidant activity and M. oleifera leave protein is an important active ingredient in the aqueous extract.
Liang Tao   +13 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Comparison of cytotoxicity, antioxidation and hypoglycemic activity of three stilbene compounds

open access: yesShipin yu jixie
ObjectiveTo explore the differences in cytotoxicity, antioxidant, and hypoglycemic activities of resveratrol, oxy-resveratrol, and piceatannol, three stilbene compounds with similar structures.MethodsThe cytotoxicity, extracellular/intracellular ...
CHEN Ying   +4 more
doaj   +1 more source

Antioxidant activity of phenolic compounds

open access: yesGrasas y Aceites, 1993
This review deals with the oxidation processes induced by light and atmospheric oxygen, as well as the protective action on antioxidant compounds. The available data on the synthetic antioxidants and the problems associated to their use, together with ...
R. Maestro Durán, R Borja Padilla
doaj   +1 more source

Determination of antioxidant activity and phenolic compounds in different Mexican craft beers

open access: yes, 2022
The objective of the present study was to evaluate and compare the phenolic content (total phenols and flavonoids) and the antioxidant capacity of seventeen craft beers produced in Mexico.
Mendez-Trujillo, Vianey   +3 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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