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Enhancing 5‐aminolevulinic acid tolerance and production by engineering the antioxidant defense system of Escherichia coli

Biotechnology and Bioengineering, 2019
5‐Aminolevulinic acid (ALA) is a value‐added compound with potential applications in the fields of agriculture and medicine. Although massive efforts have recently been devoted to building microbial producers of ALA through metabolic engineering, few ...
Chengchao Zhu   +8 more
semanticscholar   +1 more source

Antioxidant defense systems of two lipidopteran insect cell lines

Free Radical Biology and Medicine, 2001
Spodoptera frugiperda Sf-9 (Sf-9) and Trichoplusia ni BTI-Tn-5B1-4 (Tn-5B1-4) insect cell lines were found to contain unique assemblages of antioxidant enzymes. Specifically, the Sf-9 insect cell line contained Manganese and Copper-Zinc superoxide dismutase (MnSOD and CuZnSOD) for reducing the superoxide radical (O(2)(*-)) to hydrogen peroxide (H(2)O(2)
Y, Wang, L W, Oberley, D W, Murhammer
openaire   +2 more sources

Age-dependent modifications in rat hepatocyte antioxidant defense systems

Journal of Hepatology, 1997
Age-dependent changes in the hepatic antioxidant systems were studied in hepatocytes from newly weaned (21 days) to 30-month-old rats.Biphasic changes were observed in superoxide dismutase (SOD), glucose-6-phosphate dehydrogenase (G6PDH) and malic enzyme (ME), in which noticeable decreases were detected in hepatocytes from newly weaned to 6-month-old ...
N, Sanz   +3 more
openaire   +2 more sources

Chromium (VI) Can Activate and Impair Antioxidant Defense System

Biological Trace Element Research, 2010
The changes in glutathione-dependent cycle enzymes and catalase activities under Cr(VI)-induced oxidative stress were investigated in two distinct cell lines: L-41-human epithelial-like cells and HLF-fetal human diploid lung fibroblasts, which differ in tissue origin, proliferation, and antioxidant enzymes activities. The chromium concentrations from 1
Nino, Asatiani   +4 more
openaire   +2 more sources

Ubiquinone redox cycle as a cellular antioxidant defense system

BioFactors, 1999
AbstractUbiquinone (UQ) reductase responsible for reduction of non‐mitochondrial UQ was investigated in rats toward demonstrating an antioxidant role of UQ. In the liver, most of cellular UQ‐10 reductase activity was attributable to a novel NADPH‐UQ reductase in cytosol.
T, Kishi   +3 more
openaire   +2 more sources

Selenoproteins are involved in antioxidant defense systems in thalassemia

Metallomics, 2017
Thalassemia major (TM) is a hereditary blood disease that affects the production of hemoglobin, resulting in severe anemia.
G. E. Genc, Z. Ozturk, S. Gumuslu
openaire   +2 more sources

The Role of the Antioxidative Defense System in Papulopustular Acne

The Journal of Dermatology, 2001
AbstractAcne vulgaris frequently occurs in the second decade of life. The pathogenesis of the disease is multifactorial. In this study, we aimed to investigate the role of reactive oxygen species in inflammation of acne by determining the activity of antioxidant defense enzymes in leukocytes.
Kilinc, I, Gultekin, F, Basak, PY
openaire   +4 more sources

A Secondary Antioxidant Defense Role for Proteolytic Systems

1988
Free radicals, and related oxidants, have long been studied as agents of tissue damage. Lipid peroxidation is a well-established example of free radical toxicity, as is oxidative damage to RNA, DNA, and even carbohydrates. In contrast, the reactions of proteins with various radicals/oxidants have not been so extensively studied and it is sometimes ...
openaire   +2 more sources

Antioxidants: Responses and Importance in Plant Defense System

2020
Antioxidants are chemical substances that prevent cell damage during different stress. Antioxidants are found in all the form of foods, including fruits and vegetables. Although oxidation reactions are crucial, this might cause damage to life. Antioxidants (glutathione, vitamin E, C, etc.) and various other enzymes (superoxide dismutase, catalase ...
Narendra Kumar   +2 more
openaire   +1 more source

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