Results 111 to 120 of about 7,172,362 (315)

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Antioxidant activity of inhibitor of angiotensin-converting enzyme in kidney

RUDN Journal of Medicine, 2009
The influence of inhibition of angiotensin-converting enzyme on free-radical processes in kidney cell is investigated at different models of acute renal failure. It is established antioxidant effect of captopril in kidneys of rats.
Y A Belous, I A Komarevtseva, K V Komarevtseva   +2 more
doaj  

House dust-mites: effect on antioxidant enzyme activities.

Medical science monitor : international medical journal of experimental and clinical research, 2006
House dust-mites are potent allergens of the indoor environment and are common inhabitants of houses worldwide. Free radicals are constantly produced by cells, mostly as reactive oxygen species. Once produced, free radicals are removed by antioxidant defenses, including the enzymes SOD, GPx, and CAT.The aim was to describe the importance of the ...
ATAMBAY, Metin, KARABULUT, Aysun Bay, Yazar, Süleyman, Kilic, Eser, DALDAL, Nilgun, Saraymen, Recep, KARAMAN, Ulku   +6 more
openaire   +3 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Ischemia vs Reperfusion : effects on expression and activity of antioxidant enzyme systems and oxidative damage

, 2004
Ischemia vs Reperfusion : effects on expression and activity of antioxidant enzyme systems and oxidative ...
G Harrison (9872774), Kylie Venardos (13053762), A Perkins (9877679), J Headrick (13669258), K Ashton (13701529)   +4 more
core  

The Effect of Seed Pod Removal on Salinity Tolerance of Annual Medic (Medicago scutellata) at the Germination Stage

پژوهش‌های بذر ایران, 2016
There have been a few studies on removing the seed pods in annual medics, despite its importance. To investigate the role of pod removal on seed germination, seedling growth and antioxidant enzyme activities in annual medic (Medicago scutellata L.) Under
Farzaneh Fakhari, Hossein Sadeghi
doaj   +2 more sources

Effect of Aqueous Extract of Allium Canadense on the Activity of the Inhibited Acetylcholinesterase Enzyme by Organophosphate Diazinon

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2022
Introduction: Allium genus with more than 900 important breeding and wild species, as a natural and bioactive antioxidant, is widely used in the pharmaceutical and food industries.
Mino Asadi, Faranak Hadi, Seyed Hesamuddin Hejazi, Farideh Azarbani   +3 more
doaj  

Pot Level Drought Stress Tolerance Assay in Tobacco through Plant Phenotyping and Antioxidant Assay

Bio-Protocol, 2015
Drought is an important abiotic factor which has a huge detrimental impact on crop productivity. Study of plant responses towards drought stress and investigating the mechanism of drought tolerance is crucial for achieving the target of developing ...
Priyanka Das, Nita Lakra, Kamlesh Nutan, Sneh Singla-Pareek, Ashwani Pareek   +4 more
doaj   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Phytochemistry and biological activity of Onosma rascheyana extracts (Boiss.)

International Journal of Plant Based Pharmaceuticals, 2022
In recent years, it has been determined that Onosma species exhibit interesting biological/pharmacological activities. The aim of this study was to analyze the chemical composition, antioxidant and enzyme inhibitory activities of the methanol (MeOH ...
Cengiz Sarikurkcu, Ersin Demir, Mehmet Sabih Ozer, Riza Binzet   +3 more
doaj