Results 201 to 210 of about 7,172,362 (315)

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Antioxidant Enzyme Activity and Serum HSP70 Concentrations in Relation to Insulin Resistance and Lipid Profile in Lean and Overweight Young Men. [PDF]

Antioxidants (Basel), 2023
Lubkowska A, Dudzińska W, Pluta W.
europepmc   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Mycorrhizal Inoculation Enhances Drought Tolerance in Potato (Solanum tuberosum L.) by Modulating Antioxidant Enzyme Activity and Related Gene Expression. [PDF]

Biology (Basel)
Ettlili S, Aroca R, Djebali N, Labidi S, Jeddi FB.   +4 more
europepmc   +1 more source

Molecular Research of Lipid Peroxidation and Antioxidant Enzyme Activity of Comamonas testosteroni Bacterial Cells under the Hexachlorobenzene Impact. [PDF]

Int J Mol Sci, 2022
Dimova M, Tugai A, Tugai T, Iutynska G, Dordevic D, Kushkevych I.   +5 more
europepmc   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

Blue Light and Methyl Jasmonate Synergistically Enhance Betalain Accumulation, Antioxidant Enzyme Activity, and Osmotic Adjustment in Sugar Beet (<i>Beta vulgaris</i> L.) Seedlings: A Time-Course Analysis. [PDF]

Plants (Basel)
Wang H, Yang C, Yu Y, Cheng D, Dai C, Luo C.   +5 more
europepmc   +1 more source

The Aqueous Extract of Brassica oleracea L. Exerts Phytotoxicity by Modulating H₂O₂ and O₂^- Levels, Antioxidant Enzyme Activity and Phytohormone Levels. [PDF]

Plants (Basel), 2023
Wang Y, Zhao Y, Dong B, Wang D, Hao J, Jia X, Zhao Y, Nian Y, Zhou H.   +8 more
europepmc   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

Influence of Cutting Styles on Antioxidant Capabilities of Fresh-Cut Cauliflower by Regulating ROS Metabolism and Antioxidant Enzyme Activity. [PDF]

Antioxidants (Basel)
Guo Q, Li B, Wang J, Shi M, Wang J, Chen Y, Zhang Y, Sarengaowa, Xiao Y, Feng K.   +9 more
europepmc   +1 more source