Results 261 to 270 of about 523,877 (311)

Antioxidant Enzymes and Apoptosis

Drug Metabolism Reviews, 2004
The role of antioxidant enzymes can be interpreted in terms of fine tuning of the concentration of reactive oxygen species which are required in the redox regulation of the cell cycle and of programmed cell death. This review summarizes findings from papers published in the last few years which deal with the relation between apoptosis and the two ...
Regine, Kahl, Andreas, Kampkötter, Wim, Wätjen, Yvonni, Chovolou   +3 more
openaire   +2 more sources

Antioxidant Enzymes and Diabetic Retinopathy

Annals of the New York Academy of Sciences, 2007
Abstract:  The aim of this study was to discuss the serum copper (Cu), zinc (Zn), nitric oxide (NO), glutathione (GSH), advanced oxidation protein products (AOPP) levels, and superoxide dismutase (SOD) activities with diabetic retinopathy severity.
Guersel, E., Yildirim, Zuhal, Ucgun, N. Irem, Kilic, Nedret, Sepici-Dincel, AYLİN   +4 more
openaire   +3 more sources

Antioxidant Enzyme Mimics with Synergism

Mini-Reviews in Medicinal Chemistry, 2010
The antioxidant enzymes, such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione S-transferase contribute dominatingly to enhance cellular antioxidant defense against oxidative stress. They act cooperatively to scavenge reactive oxygen species, and not one of them can singlehandedly clear all forms of reactive oxygen species. On
Fei, Yan, Ying, Mu, Ganglin, Yan, Junqiu, Liu, Jiacong, Shen, Guimin, Luo   +5 more
openaire   +2 more sources

Antioxidant enzymes and human diseases

Clinical Biochemistry, 1999
To describe the importance of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, and catalase working together in human cells against toxic reactive oxygen species, their relationship with several pathophysiologic processes and their possible therapeutic implications.Reactive oxygen species (ROS) are involved in the cell growth ...
J M, Matés, C, Pérez-Gómez, I, Núñez de Castro   +2 more
openaire   +2 more sources

Antioxidant Enzymes in Human Tears

Journal of Ocular Pharmacology and Therapeutics, 1991
Minimally stimulated tear samples collected from human subjects were assayed for the major antioxidant enzymes: superoxide dismutase, catalase and glutathione peroxidase. No catalase or glutathione peroxidase activity was detected. However, human tear film does contain the CuZn superoxide dismutase (103 +/- 32 ng/mg soluble protein), which is ...
R K, Crouch, P, Goletz, A, Snyder, W H, Coles   +3 more
openaire   +2 more sources

Pre-exercise antioxidant enzyme activities determine the antioxidant enzyme erythrocyte response to exercise

Journal of Sports Sciences, 2005
Free radical production increases during exercise and oxidative damage occurs in several tissues. We examined the effects of three different exercise tests on the pattern of change of erythrocyte enzyme antioxidant activities. The tests were a short maximal exercise test, a submaximal prolonged exercise test and a cycling stage during competition.
P, Tauler, A, Aguiló, P, Guix, F, Jiménez, G, Villa, J A, Tur, A, Córdova, A, Pons   +7 more
openaire   +2 more sources

Regulation of Antioxidant Enzymes

The Journal of Nutrition, 1992
Free radicals generated by a partial reduction of O2 pose a serious hazard to tissues and vital organs, especially membrane lipids, connective tissues, and the nucleic acids of cells. For protection, enzymes have evolved that specifically attack O2-, hydrogen, and organic peroxides, and repair any damage incurred to DNA.
openaire   +3 more sources

Antioxidant enzymes in oral verrucous carcinoma

Journal of Oral Pathology & Medicine, 2016
BackgroundVerrucous carcinoma is a non‐metastasizing variant of welldifferentiated squamous cell carcinoma, which has been associated with reactive oxygen species generated by betel quid chewing. Salivary antioxidant systems have been suggested to play a protective role in reducing the oxidative damage.
Ting-Ying, Fu, Meng-Han, Tsai, Jyh-Seng, Wang, Luo-Ping, Ger   +3 more
openaire   +2 more sources

Caloric restriction, aging, and antioxidant enzymes

Mutation Research/DNAging, 1993
The basic mechanisms of aging and its retardation by caloric restriction (CR) remain unclear. One suggested means by which CR could retard aging is based on production of mitochondrial free radicals, and efficiency of their subsequent metabolism. Currently, there is little information concerning the influences of age and CR on the rates of in vivo ...
R J, Feuers, R, Weindruch, R W, Hart
openaire   +2 more sources

Antioxidant and redox enzymes in radioprotection

Pharmacology & Therapeutics, 1988
Abstract In summary, there are theoretically several ways by which a cell's content of DNA repair genes or other radioprotective proteins can be increased. At present the most feasible way to do so seems to be to search for repair systems, such as the adaptive repair observed in human lymphocytes, whose activity can be increased by exogenous inducing
J E, Biaglow, M E, Varnes, E R, Epp, E P, Clark   +3 more
openaire   +2 more sources