In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Developmental stage is an important factor that determines the antioxidant responses of young and old grapevine leaves under UV irradiation in a green-house. [PDF]
The impact of UV irradiation was studied on photosynthesis, photosystem II photochemical yields and antioxidant responses using green-house grown grapevine (Vitis vinifera L. cv. Chardonnay) leaves.
Éva Hideg +3 more
core +2 more sources
Antioxidant potential of green leafy porridges [PDF]
To evaluate the antioxidant potential of porridges (kola kenda) made incorporating herbs.Experimental study. Main outcome measures Total phenolic content was estimated by Folin Ciocalteau method (GAEmg/g(FW) and the antioxidant potential by ABTS free radical scavenging activity (TEAC(μg)/100g (FW).Total phenolics and antioxidant potentials of porridges
S P A S, Senadheera +2 more
openaire +2 more sources
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
THE ANTIOXIDANT POTENTIAL OF PROPOFOL (2,6-DIISOPROPYLPHENOL) †
We have examined in vitro the antioxidant properties of 2,6-diisopropylphenol. In studies using electron spin resonance spectroscopy we have demonstrated that 2,6-diisopropylphenol acts as an antioxidant by reacting with free radicals to form a phenoxyl radical--a property common to all phenol-based free radical scavengers.
P G, Murphy +4 more
openaire +2 more sources
An antioxidant activity which changed by the variety of food [PDF]
Taros was found to be a very effective antioxidant in several food. In the present study, the antioxidant activity of one food was compared to that of two kinds of food. The activity was elevated with hot pepper (shichimi) and beer yeast.
ドウケ, ショウコ +2 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Antimicrobial and antioxidant potential of endophytic fungi isolated from ethnomedicinal plants of Western Ghats, Karnataka [PDF]
A total of 79 endophytic fungal isolates were obtained from four wild medicinal plants -Tinospora cordifolia (Willd.) Hook.f and Thomson (Menispermaceae), Piper nigrum L., Piper longum L.
Srinivas Chowdappa +3 more
core +1 more source
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Evaluation of Antioxidant Potential of Melanthera scandens
A methanol extract of dried leaves of Melanthera scandens was examined for antioxidant activities using a variety of assays, including 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power, ferrous chelating, and ferric thiocyanate methods with ascorbic acid and EDTA as positive controls. The extract showed noticeable activities in most
Adesegun, Sunday Adeleke +3 more
openaire +2 more sources

