Results 161 to 170 of about 618,778 (269)

Seasonal Variation in Bivalve Antioxidant Enzymes: Can they be used as indicators of heavy metal contamination?

open access: yes, 2009
Seasonal variations in the activity of several enzymes (glutathione reductase (GR), glutathione S-transferase (GST), and glutathione peroxidase (GPx)) involved in the glutathione cellular defence system were measured in whole tissues of the common New ...
Gibson, Aimee Clare
core  

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi   +15 more
wiley   +1 more source

Antioxidant potential of microencapsulated bioactive extracts from durian fruit's pulp, seed, and peel as food additives. [PDF]

open access: yesFront Nutr
Velazquez-Martinez V   +7 more
europepmc   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

open access: yesAdvanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi   +15 more
wiley   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

open access: yesAdvanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng   +17 more
wiley   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Exploring the antioxidant potential of prolactin. [PDF]

open access: yesFront Pharmacol
Bulut Arikan F, Sagsoz N.
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Apple Pomace as a Promising By-Product with High Antioxidant Potential in the Prevention of Aging Processes. [PDF]

open access: yesFoods
Wysocki K   +5 more
europepmc   +1 more source

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