Results 121 to 130 of about 469,363 (168)

Enzymatic antioxidant system of endotheliocytes

Doklady Biochemistry and Biophysics, 2016
It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the "classic" antioxidant enzymes (Cu,Zn-superoxide dismutase, catalase, and Se-containing glutathione peroxidase). At the same time, a high expression level of peroxiredoxin genes was identified in the same endothelial cells, which obviously ...
M G, Sharapov, R G, Goncharov, A E, Gordeeva, V I, Novoselov, O A, Antonova, A K, Tikhaze, V Z, Lankin   +6 more
openaire   +2 more sources

The Insulin System: Influence of Antioxidants

Journal of the American College of Nutrition, 1998
At the annual meeting of the American College of Nutrition held in San Francisco in 1996, a symposium was held concerning the role of disturbed glucose/insulin homeostasis in the pathogenesis of va...
openaire   +2 more sources

The antioxidant system.

Anticancer research, 2003
The glutathione (GSH) antioxidant system is the principal protective mechanism of the cell and is a crucial factor in the development of the immune response by the immune cells. Experimental data demonstrate that a cysteine-rich whey protein concentrate represents an effective cysteine delivery system for GSH replenishment during the immune response ...
Gustavo, Bounous, John H, Molson
openaire   +1 more source

Erythrocyte antioxidant system in Down syndrome

American Journal of Medical Genetics, 2005
It has been emphasized that an increased oxidative damage can exist in Down syndrome (DS), and that superoxide dismutase (SOD-1) seems to play a role in the pathogenesis of this disorder. We have studied the antioxidant system SOD-1, catalase, glutathione peroxidase (GSH-Px) and reduced glutathione (GSH) in erythrocytes of DS adults in order to ...
G, Gerli, L, Zenoni, G F, Locatelli, R, Mongiat, F, Piattoni, G B, Orsini, A, Montagnani, M R, Gueli, V, Gualandri   +8 more
openaire   +2 more sources

Antioxidant System in Sickle Red Cells

Acta Haematologica, 2009
Erythrocytes containing abnormal haemoglobins with high affinity for red cell membrane are subjected to enhanced oxidant stress. Since HbS is known to have high affinity for red cell membrane and sickle cells are particularly susceptible to membrane lipid peroxidation, the behaviour of erythrocyte antioxidant system has been evaluated in 20 subjects ...
L, Beretta, G C, Gerli, R, Ferraresi, A, Agostoni, V, Gualandri, G B, Orsini   +5 more
openaire   +2 more sources

The effect of Irisin on antioxidant system in liver

Free Radical Biology and Medicine, 2014
Nonalcoholic fatty liver disease (NAFLD) is a global health problem and lead to subacute liver failure, cirrhosis and/or hepatocellular carcinoma. An increased generation of reactive oxygen species (ROS) and antioxidant depletion is found in the liver of obese patients with NAFLD. Irisin is a recently identified exercise-induced myokine.
Saime, Batirel, Perinur, Bozaykut, Ergül, Mutlu Altundag, Nesrin, Kartal Ozer, Christos S, Mantzoros   +4 more
openaire   +3 more sources

Salivary antioxidants in patients with systemic sclerosis

Journal of Oral Pathology & Medicine, 2013
BackgroundIn spite of relatively large amount of evidence that oxidative stress is implicated in the pathogenesis of systemic sclerosis, there is no study analyzing antioxidants profile of the saliva of these patients. The aim of this study was to compare salivary antioxidants in subjects with systemic sclerosis and the healthy controls.MethodsThe ...
Anna, Zalewska, Małgorzata, Knaś, Ewa, Gińdzieńska-Sieśkiewicz, Napoleon, Waszkiewicz, Anna, Klimiuk, Katarzyna, Litwin, Stanisław, Sierakowski, Danuta, Waszkiel   +7 more
openaire   +2 more sources

Mechanism of Cisplatin Ototoxicity: Antioxidant System

Pharmacology & Toxicology, 1995
Abstract: The dose and duration limiting toxic effects of cisplatin are ototoxicity and nephrotoxicity. While several studies have attempted to shed some light on the causes of nephrotoxicity, the reasons for ototoxicity induced by cisplatin are poorly understood.
R, Ravi, S M, Somani, L P, Rybak
openaire   +2 more sources

Antioxidant System Activation in Prostate Cancer

Biological Trace Element Research, 2004
The activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) and the levels of copper, zinc, and malondialdehyde were determined in 21 age-, sex-, and body-mass-index-matched prostate cancer patients; 50 patients diagnosed with benign prostatic obstruction (BPO) were compared to 50 healthy male subjects acting as controls.
M I, Yilmaz, K, Saglam, A, Sonmez, D E, Gok, S, Basal, S, Kilic, C, Akay, I H, Kocar   +7 more
openaire   +2 more sources

Biosensors for Antioxidant Evaluation in Biological Systems

Combinatorial Chemistry & High Throughput Screening, 2013
The prevention of oxidative reactions in a biological medium as well as the role of reactive oxygen species (ROS) in chronic degenerative diseases are questions that continue to be investigated. Electrochemical biosensors have shown attractive features to evaluate the oxidative stress condition at a level comparable to chromatographic and spectroscopic
Lucilene Dornelles, Mello, Alexandre, Kisner, Marilia Oliveira Fonseca, Goulart, Lauro Tatsuo, Kubota   +3 more
openaire   +2 more sources