Results 291 to 300 of about 24,048,620 (390)

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

24-Epibrassinolide Enhanced Plant Antioxidant System and Cadmium Bioavailability Under Soil Cadmium Stress. [PDF]

Plants (Basel)
Song W, Li H, Zhao Z, Si R, Deng W, Wang M, Li Y.   +6 more
europepmc   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Nitric oxide regulates photosynthesis and the capacity of the antioxidant system under water deficit and rehydration in <i>Lolium multiflorum</i>/<i>Festuca arundinacea</i> introgression forms. [PDF]

Front Plant Sci
Perlikowski D, Lechowicz K, Blicharz S, Arasimowicz-Jelonek M, Czapiewska A, Pawłowicz I, Kosmala A.   +6 more
europepmc   +1 more source

Effect of Farming System Type on Broilers’ Antioxidant Status, Performance, and Carcass Traits: An Industrial-Scale Production Study [PDF]

Evgenia Fotou, Vasiliki Moulasioti, Georgios Α. Papadopoulos, Dimitra Kyriakou, Maria-Eleni Boti, Vassilios Moussis, Maria Papadami, Constantinos C. Tellis, Apostolos Patsias, Ioannis Sarrigeorgiou, Alexandros Theodoridis, Peggy Lymberi, Vasilios Tsiouris, Vassilios Tsikaris, Demokritos Tsoukatos   +14 more
openalex   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Response of the photosynthetic characteristics and antioxidant system of Suaeda salsa to the changes of underground brine depth. [PDF]

Front Plant Sci
Wang P, Xu W, Zhang Z, Fu Z, Li T, Sun J.   +5 more
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System. [PDF]

Diabetes Metab J
Park IR, Chung YG, Won KC.
europepmc   +1 more source

A study of Some Hormones and Antioxidant Systems Disturbances in Older Men

, 2018
R. Alsaadi, Dakhel Ghani Omran AL-Watify
openalex   +1 more source