Results 91 to 100 of about 28,158 (212)
Physapubescin B may interfere with multiple cancer‐associated signaling pathways by inhibiting Ras/Raf/mitogen‐activated protein kinase kinase/extracellular signal‐regulated kinase (Ras/Raf/MEK/ERK) signaling and vascular endothelial growth factor (VEGF)‐dependent angiogenesis.
Wojciech Koch +11 more
wiley +1 more source
ABSTRACT Background and Aims Scabies is a highly contagious parasitic skin disease and neglected tropical disease disproportionately affecting populations in poverty and fragile health systems. In Afghanistan, evidence on its environmental and socioeconomic determinants remains scarce.
Matiullah Alimzai +10 more
wiley +1 more source
ABSTRACT In this study, we test the theory of strong‐ties and weak‐ties rationalities (STWTR) (Sundararajan 2020) and the criterion validity of its measures using strong‐ties rationality and weak‐ties rationality scales to predict COVID‐19 related perceptions and behaviours.
Rachel Sing‐Kiat Ting +7 more
wiley +1 more source
ABSTRACT Rare adverse drug reactions (ADRs) are underrecognized and underreported in the electronic medical record (EMR). These events often require clinical review, making systematic identification challenging. The study aim was to develop an approach to prioritize identification and validation of a rare ADR to trimethoprim‐sulfamethoxazole causing ...
Keith Feldman +6 more
wiley +1 more source
Hops essential oil (HEO), a by-product of the brewing industry, has known antibacterial and antifungal properties, but its antiparasitic effects remain underexplored.
Danielle F. Aycart +3 more
doaj +1 more source
Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley +1 more source
Antimicrobial Effects of Quebrachitol: A Systematic Review
Quebrachitol, an optically active cyclitol derived from plants, has recently gained attention as a potential natural product with therapeutic properties, though its antimicrobial effects remain unclear. This systematic review aims to determine, appraise,
Doris Evelyn Yah Hui Jong +8 more
doaj +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley +1 more source
A series of 5‐nitroimidazole‐1,2,3‐triazole hybrids was synthesised and evaluated for antitrypanosomatid activity to assess their potential as treatments against leishmaniasis and trypanosomiasis. No notable in vitro activity against Leishmania was detected.
Liandi Ferreira +4 more
wiley +1 more source

