Results 111 to 120 of about 40,838 (333)

Antiparasitic activity of ivermectin: Four decades of research into a "wonder drug".

open access: yesEuropean journal of medicinal chemistry, 2023
Michał Sulik   +3 more
semanticscholar   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

open access: yesThe FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte   +9 more
wiley   +1 more source

Screening for Trypanosoma cruzi infection (Chagas disease) in the Latin American population living with HIV in London

open access: yesHIV Medicine, EarlyView.
Abstract Background There are an estimated 2482 people born in Latin American countries receiving care for HIV in the United Kingdom. Although national guidance recommends screening for Trypanosoma cruzi infection (Chagas disease) in this population, there is no formal screening programme.
Natalie Elkheir   +18 more
wiley   +1 more source

Molecular mechanisms of mitochondria-mediated ferroptosis: a potential target for antimalarial interventions

open access: yesFrontiers in Cell and Developmental Biology
Ferroptosis is an iron-dependent form of regulated cell death characterized by glutathione (GSH) depletion, glutathione peroxidase 4 (GPX4) inactivation, and the build-up of lipotoxic reactive species.
Adegbolagun Grace Adegboro   +2 more
doaj   +1 more source

Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of Sparicotyle chrysophrii in Gilthead Sea Bream

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream (Sparus aurata) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, like formalin, face growing regulatory restrictions, there is an urgent need for alternative control ...
Teresa Pirollo   +8 more
wiley   +1 more source

Bath Treatments With Emamectin Benzoate Control Dactylogyrideans Infecting Colossoma macropomum Gills Without Altering Physiology of This Host Fish

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Intensification of fish aquaculture worldwide has led to severe problems of diseases caused by parasitic dactylogyrideans. In this study, the anti‐dactylogyridean efficacy of treating Colossoma macropomum with baths of emamectin benzoate (EMB) was investigated for the first time, along with the effects of this treatment on the haematology and ...
Raimundo Rosemiro de Jesus Baia   +4 more
wiley   +1 more source

Total phenolic, flavonoid, flavonol, and tannin contents as well as antioxidant and antiparasitic activities of aqueous methanol extract of Alhagi graecorum plant used in traditional medicine: Collected in Riyadh, Saudi Arabia

open access: yesOpen Chemistry
Geographical and ecological variations lead to distinct chemical compositions, even among the same species of plant. Medicinal plants present promising alternatives for antiparasitic treatments.
Aljawdah Hossam M.   +4 more
doaj   +1 more source

Epidemiology of Salmonid Rickettsial Septicemia (SRS) in Farmed Salmon: The Role of Sea Lice Infestations in Mortality Risk

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Piscirickettsia salmonis , the causal agent of salmonid rickettsial septicemia (SRS), is the main pathogen affecting farmed salmonids in Chile. Outbreaks of SRS lead to substantial economic losses for producers. Many determinants related to SRS outcomes are still poorly understood.
Benjamín Diethelm‐Varela   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy