Results 71 to 80 of about 40,838 (333)

The Phylum Bryozoa: From Biology to Biomedical Potential

Marine Drugs, 2020
Less than one percent of marine natural products characterized since 1963 have been obtained from the phylum Bryozoa which, therefore, still represents a huge reservoir for the discovery of bioactive metabolites with its ~6000 described species.
Maria Letizia Ciavatta, Florence Lefranc, Leandro M. Vieira, Robert Kiss, Marianna Carbone, Willem A. L. van Otterlo, Nicole B. Lopanik, Andrea Waeschenbach   +7 more
doaj   +1 more source

Antiparasitic Potential of Chromatographic Fractions of Nephrolepis biserrata and Liquid Chromatography-Quadrupole Time-of-Flight-Mass Spectrometry Analysis

Molecules, 2021
Marine aquaculture development is recently impeded by parasitic leech Zeylanicobdella arugamensis (Hirudinea, Piscicolidae) in Sabah, Malaysia. The parasitic leech infests a variety of cultured fishes in aquaculture facilities.
M. D. Shah, K. Tani, Y. Yong, F. Ching, S. R. M. Shaleh, C. Vairappan, B. A. Venmathi Maran   +6 more
semanticscholar   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, EarlyView.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

Porphyrin Derivative Nanoformulations for Therapy and Antiparasitic Agents

Molecules, 2020
Porphyrins and analogous macrocycles exhibit interesting photochemical, catalytic, and luminescence properties demonstrating high potential in the treatment of several diseases. Among them can be highlighted the possibility of application in photodynamic
D. Deda, B. Iglesias, Eduardo Alves, K. Araki, Célia R. S. Garcia   +4 more
semanticscholar   +1 more source

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

Chemistry &Biodiversity, EarlyView.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel, Ângela Liberal, Tiane C. Finimundy, Tânia S. P. Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M. Romeiras, Ângela Fernandes   +9 more
wiley   +1 more source

Efficacy of Diterpene Polyalthic Acid Combined with Amphotericin B against Leishmania amazonensis In Vitro

Pharmaceuticals
Background/Objectives: Leishmaniasis, a neglected disease caused by Leishmania spp. including L. amazonensis, urgently requires new treatments. Polyalthic acid (PA), a natural diterpene from Copaifera spp., has previously demonstrated significant ...
Ana Carolina Bolela Bovo Candido, Mariana Cintra Pagotti, Daiane Albino dos Santos, Lucas Antonio de Lima Paula, Rodrigo Cássio Sola Veneziani, Jairo Kenupp Bastos, Sérgio Ricardo Ambrósio, Lizandra Guidi Magalhães   +7 more
doaj   +1 more source

Mānuka Oil—A Review of Antimicrobial and Other Medicinal Properties

Pharmaceuticals, 2020
Mānuka oil is an essential oil derived from Leptospermum scoparium, a plant that has been used by the indigenous populations of New Zealand and Australia for centuries.
Cynthia Mathew, Wubshet Tesfaye, Phil Rasmussen, Gregory M Peterson, Andrew Bartholomaeus, Manab Sharma, Jackson Thomas   +6 more
doaj   +1 more source

The Antimicrobial Potential of the Neem Tree Azadirachta indica

Frontiers in Pharmacology, 2022
Azadirachta indica (A. Juss), also known as the neem tree, has been used for millennia as a traditional remedy for a multitude of human ailments. Also recognized around the world as a broad-spectrum pesticide and fertilizer, neem has applications in ...
Marina R. Wylie, D. Scott Merrell
doaj   +1 more source

Copper(II), a Peculiar Metal Ion for Complexation with Monensin A Ionophore

Chemistry – A European Journal, EarlyView.
Copper(II) forms three chiral and EPR‐active complexes with monensinate A in methanol. Beside the bis [CuL2] and mono [CuL]+ species, the new dinuclear construct [Cu2L]3+ exhibits an [ML]+‐type and a metal salt‐type copper(II) centers weakly bound to each other through counter ion(s) and thus, being magnetically independent.
Máté Levente Kis, Bálint Hajdu, Tamás Jakusch, Zoltán Kele, Petar Dorkov, Rositsa Kukeva, Ivayla Pantcheva, Béla Gyurcsik   +7 more
wiley   +1 more source

Conjugates Containing Two and Three Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Units as In Vitro Antiparasitic and Anticancer Agents

Pharmaceuticals, 2020
The synthesis, characterization, and in vitro antiparasitic and anticancer activity evaluation of new conjugates containing two and three dinuclear trithiolato-bridged ruthenium(II)-arene units are presented.
Valentin Studer, Nicoleta Anghel, Oksana Desiatkina, Timo Felder, Ghalia Boubaker, Yosra Amdouni, Jessica Ramseier, Martin Hungerbühler, Christoph Kempf, Johannes Thomas Heverhagen, Andrew Hemphill, Nico Ruprecht, Julien Furrer, Emilia Păunescu   +13 more
doaj   +1 more source